University of Massachusetts Chan Medical School

The UMass Chan Medical School is a public medical school in Worcester, Massachusetts, and the health-sciences campus of the University of Massachusetts system, with schools of medicine, biomedical sciences and nursing.马萨诸塞大学陈医学院是位于马萨诸塞州伍斯特的一所公立医学院，也是马萨诸塞大学系统的健康科学校区，下设医学院、生物医学研究生院与护理研究生院。

It was established by the Massachusetts legislature in 1962, admitted its first sixteen medical students in 1970, and took its present name in 2021 after a 175 million dollar gift from the family of the Hong Kong developer Chan Tseng-hsi.该校由马萨诸塞州议会于 1962 年立法设立，1970 年招收首批 16 名医学生，2021 年在获得香港地产商陈曾熙家族 1.75 亿美元捐赠后改用现名。

UMass Chan occupies the 201-300 band of the 2026 Academic Ranking of World Universities, ranks 460th in the 2026-2027 U.S. News global table, and appears in neither the 2027 Times Higher Education nor the 2027 QS world ranking.该校在 2026 年软科世界大学学术排名中处于第 201 至 300 名区间，在 2026 至 2027 年度 U.S. News 全球大学排名中位列第 460 位，未进入 2027 年泰晤士高等教育世界大学排名，也未进入 2027 年 QS 世界大学排名。

History

• The 162nd Massachusetts General Court created the University of Massachusetts Medical School in 1962, and Governor John Volpe signed the legislation into law.1962 年，第 162 届马萨诸塞州议会设立马萨诸塞大学医学院，州长约翰·沃尔普签署法案使其生效。
• The founding purpose was twofold: to let residents of the commonwealth study medicine at an affordable cost and to increase the number of primary-care physicians working in under-served areas.建校目的有两重：让本州居民能以可负担的成本学医，并增加在医疗服务不足地区执业的全科医生数量。
• Lamar Soutter, the school's founding dean, shaped a curriculum oriented towards community and primary care rather than towards a research-intensive academic medical centre.首任院长拉马尔·苏特确立了面向社区与初级医疗的课程方向，而非以科研密集的学术医学中心为模板。
• The School of Medicine admitted its first class of sixteen students in 1970, eight years after the legislature authorised the school and four years before its hospital existed.医学院于 1970 年招收首批 16 名学生，此时距州议会立法授权已过八年，而学校自己的医院还要四年后才建成。
• A 371-bed teaching hospital opened on the Worcester campus in 1976, giving the school its own clinical base and ending its dependence on borrowed wards.1976 年，一座拥有 371 张床位的教学医院在伍斯特校区落成，使学校拥有了自己的临床基地，不再依赖借用病区。
• The Graduate School of Biomedical Sciences opened in 1979 with a first class of seven students and went on to award more than a thousand PhDs.生物医学研究生院于 1979 年开办，首届仅 7 名学生，此后累计授予博士学位逾一千个。
• The Graduate School of Nursing opened in 1986 and has since awarded more than six hundred master's, post-master's and doctoral degrees in nursing.护理研究生院于 1986 年开办，此后累计授予护理硕士、硕士后与博士学位六百余个。
• In 1997 the school acquired the Worcester Foundation for Biomedical Research in Shrewsbury, the laboratory where the combined oral contraceptive pill was developed in the early 1960s.1997 年，学校收购了位于什鲁斯伯里的伍斯特生物医学研究基金会，该实验室曾在 1960 年代初研发出复方口服避孕药。
• In 1998 the university's hospitals and clinics merged with Memorial Health Care to form UMass Memorial Health Care, the largest provider in Central Massachusetts and the school's clinical partner.1998 年，该校的医院与诊所系统与纪念医疗合并，组建马萨诸塞大学纪念医疗集团，成为马萨诸塞州中部最大的医疗服务提供者与该校的临床伙伴。
• The Aaron Lazare Medical Research Building, a ten-storey laboratory named for the chancellor emeritus, opened in October 2001 to house more than 260 investigators.以荣休校监阿伦·拉扎尔命名的拉扎尔医学研究大楼于 2001 年 10 月启用，这座十层实验楼可容纳 260 多名研究人员。
• In 2009 Victor Ambros, Craig Mello, Melissa Moore and Phillip Zamore founded the RNA Therapeutics Institute, which became a full academic department in 2016.2009 年，维克托·安布罗斯、克雷格·梅洛、梅利莎·摩尔与菲利普·扎莫尔共同创办 RNA 治疗研究所，该所于 2016 年成为正式的学术系。
• On 30 January 2013 the Albert Sherman Center, a 512,000 square foot research and education building, opened in a ceremony attended by Governor Deval Patrick.2013 年 1 月 30 日，面积 51.2 万平方英尺的阿尔伯特·舍曼中心举行启用仪式，州长德瓦尔·帕特里克出席。
• Beginning with the entering class of 2016, the school dropped the requirement that degree candidates, other than MD-PhD students, be Massachusetts residents.自 2016 级新生起，学校取消了除医学博士与哲学博士联合学位学生外、学位候选人必须是马萨诸塞州居民的规定。
• In 2021 an unrestricted 175 million dollar gift from the family of Chan Tseng-hsi, a Hong Kong real estate developer, renamed the medical school and its biosciences and nursing schools.2021 年，香港地产商陈曾熙家族捐赠 1.75 亿美元不设用途限制的款项，医学院及其生物医学、护理两所研究生院因此更名。
• The gift produced the present three-school naming: the T.H. Chan School of Medicine, the Morningside Graduate School of Biomedical Sciences and the Tan Chingfen Graduate School of Nursing.这笔捐赠造就了今天三所学院的命名：T.H. Chan 医学院、Morningside 生物医学研究生院与 Tan Chingfen 护理研究生院。
• The 1976 hospital, the 1979 biomedical graduate school and the 1986 nursing school established, in that order, the three-part structure that the campus still uses.1976 年的医院、1979 年的生物医学研究生院与 1986 年的护理研究生院，按此顺序奠定了校园沿用至今的三部分结构。
• Research grants and contracts grew from about two million dollars in 1977 to more than 322 million dollars in 2022, an increase of over sixteen thousand per cent in forty-five years.科研拨款与合同额从 1977 年的约 200 万美元增至 2022 年的逾 3.22 亿美元，四十五年间增幅超过一万六千个百分点。
• MassBiologics traces its origin to the University of Massachusetts Biologic Laboratory of 1894, was re-established by the legislature in 1997 and passed from the Department of Public Health to the medical school.马萨诸塞生物制品所的历史可追溯至 1894 年的马萨诸塞大学生物制品实验室，1997 年由州议会重新设立，并从州公共卫生部划归医学院管理。
• In 2005 MassBiologics opened an eighty million dollar facility for monoclonal-antibody production, extending a public vaccine operation into modern biologic manufacturing.2005 年，马萨诸塞生物制品所启用一座造价 8000 万美元的单克隆抗体生产设施，把公共疫苗业务延伸到现代生物制品制造。
• For the 2025-2026 academic year the school rescinded every offer of admission to its biomedical graduate programmes after federal research funding was cut by the second Trump administration.2025 至 2026 学年，在第二届特朗普政府削减联邦科研经费之后，该校撤销了生物医学研究生项目的全部录取通知。

Academics

• The medical school is organised into three degree-granting schools: the T.H. Chan School of Medicine, the Morningside Graduate School of Biomedical Sciences and the Tan Chingfen Graduate School of Nursing.该校由三个授予学位的学院组成：T.H. Chan 医学院、Morningside 生物医学研究生院与 Tan Chingfen 护理研究生院。
• The T.H. Chan School of Medicine is accredited by the Liaison Committee on Medical Education and awards the MD degree, with about 165 students enrolling each year.T.H. Chan 医学院经医学教育联络委员会认证并授予医学博士学位，每年约有 165 名学生入学。
• More than 4,350 students have received medical degrees from the school since 1970, a total that reflects its deliberately small annual intake.自 1970 年以来，已有逾 4350 名学生从该校获得医学学位，这一总数反映出其刻意维持的小规模年度招生。
• The school built its reputation on primary care, and more than half of each graduating class has historically entered primary-care residencies, although that share has fallen in recent years.该校以初级医疗建立声誉，历史上每届毕业生中超过一半进入全科住院医师培训，不过这一比例近年有所下降。
• The Morningside Graduate School of Biomedical Sciences runs a PhD programme with a broad basic-medical-science background and a thesis project chosen for its relevance to human disease.Morningside 生物医学研究生院开设博士项目，要求学生具备广博的基础医学背景，并选择与人类疾病相关的课题作学位论文。
• Students in that programme choose their own curriculum and thesis mentors, and since 1979 more than a thousand have earned PhDs, beginning with the first class of seven.该项目学生可自主选择课程与论文导师，自 1979 年首届 7 人起，已有逾一千人获得博士学位。
• The Tan Chingfen Graduate School of Nursing prepares advanced practice nurses, nurse scientists and educators, and has awarded more than six hundred master's, post-master's and doctoral degrees since 1986.Tan Chingfen 护理研究生院培养高级执业护士、护理科学家与教育者，自 1986 年以来已授予六百余个护理硕士、硕士后与博士学位。
• The campus is accredited by the New England Commission of Higher Education, in addition to the professional accreditation of its medical and nursing programmes.除医学与护理项目的专业认证外，整个校区还获得新英格兰高等教育委员会的院校认证。
• Faculty research spans HIV and infectious disease, cancer, genetic disorders, diabetes and immunology, and the school's scientists established the fundamental difference between HIV and other retroviruses.教员的科研覆盖艾滋病与传染病、癌症、遗传病、糖尿病与免疫学，该校科学家确立了艾滋病病毒与其他逆转录病毒之间的根本差异。
• UMass Chan researchers also found the link between the immune system and type-1 diabetes and identified the genetic cause of the third most common form of muscular dystrophy.该校研究者还发现了免疫系统与 1 型糖尿病之间的联系，并确定了第三常见的肌营养不良症的遗传病因。
• In 1998 Craig Mello, then an investigator of the Howard Hughes Medical Institute, and Andrew Fire, then at Stanford and the Carnegie Institution, discovered RNA interference and won the 2006 Nobel Prize in Physiology or Medicine.1998 年，时任霍华德·休斯医学研究所研究员的克雷格·梅洛与当时在斯坦福大学和卡内基研究所任职的安德鲁·法尔发现了 RNA 干扰现象，并因此获得 2006 年诺贝尔生理学或医学奖。
• The RNA Therapeutics Institute, chaired by Phillip Zamore and vice-chaired by the CRISPR biologist Erik Sontheimer, brings basic scientists and clinicians together to develop RNA-based drugs.RNA 治疗研究所由菲利普·扎莫尔任所长、CRISPR 生物学家埃里克·松特海默任副所长，把基础科学家与临床医生聚合起来开发基于 RNA 的药物。
• Victor Ambros, a co-founder of that institute, shared the 2024 Nobel Prize in Physiology or Medicine for the discovery of microRNA and its role in post-transcriptional gene regulation.该所共同创办人维克托·安布罗斯因发现微小 RNA 及其在转录后基因调控中的作用，分享了 2024 年诺贝尔生理学或医学奖。
• MassBiologics is the only publicly owned, non-profit, FDA-licensed manufacturer of vaccines and other biologic products in the United States, and it supplies a substantial share of the national Td vaccine requirement.马萨诸塞生物制品所是全美唯一由公所有、非营利且持有美国食品药品监督管理局许可的疫苗与其他生物制品生产商，供应了全国很大一部分破伤风—白喉疫苗需求。
• Its monoclonal-antibody work produced actoxumab and bezlotoxumab for Clostridioides difficile infection, and with the Serum Institute of India it developed a fast-acting rabies human monoclonal antibody.其单克隆抗体研究产出了两种用于艰难梭菌感染的抗体药物，并与印度血清研究所合作开发了一种速效人源抗狂犬病单克隆抗体。
• In the 1990s Shan Lu, a professor of medicine, led DNA-based influenza vaccine work, and his team's HIV vaccine candidate generated antibody and T-cell responses in Phase I testing.1990 年代，医学教授卢山主持 DNA 流感疫苗研究，其团队的艾滋病疫苗候选物在Ⅰ期试验中使受试者产生了抗体与 T 细胞反应。
• The school also runs Commonwealth Medicine, a public-service arm that applies its clinical and analytical capacity to state health programmes and to care for underserved populations.该校还设有「联邦医疗」公共服务部门，把临床与分析能力用于州级卫生项目及对弱势群体的照护。
• Notable methodological work on the campus includes Job Dekker's chromosome conformation capture, a technique that maps how DNA folds inside the nucleus.校园内具有代表性的方法学成果包括乔布·德克尔提出的染色体构象捕获技术，该方法用于绘制细胞核内 DNA 的折叠方式。
• The school also offers combined MD-PhD training, and students on that track were exempt from the Massachusetts residency rule that applied to other degree candidates before 2016.该校还开设医学博士与哲学博士联合培养项目，该项目学生在 2016 年之前不受适用于其他学位候选人的马萨诸塞州居民规定限制。
• Its largest publicly funded cancer-research affiliate is the Quality Assurance Review Center in Lincoln, Rhode Island, which collects radiotherapy data from about a thousand hospitals for the National Cancer Institute.其最大的公共资助癌症研究附属机构是位于罗德岛州林肯的质控审查中心，该中心为美国国家癌症研究所收集约一千家医院的放射治疗数据。

Campus

• The campus stands in Worcester, the second-largest city in Massachusetts, and its hospital and clinics sit along Route 9 in the city's western and southern districts.校区位于马萨诸塞州第二大城市伍斯特，其医院与诊所沿 9 号公路分布在该市西部与南部城区。
• UMass Memorial Medical Center, the clinical partner, straddles three campuses along Route 9 plus a site in Marlborough and is designated a Level I trauma centre by the American College of Surgeons.临床伙伴马萨诸塞大学纪念医疗中心横跨 9 号公路沿线的三个园区并在马尔伯勒设有一处院区，被美国外科医师学会指定为一级创伤中心。
• The Albert Sherman Center, opened in 2013, provides 512,000 square feet of laboratory and teaching space and became the visual centre of the modern campus.2013 年启用的阿尔伯特·舍曼中心提供 51.2 万平方英尺的实验室与教学空间，成为现代校园的视觉中心。
• The Lamar Soutter Library, named for the founding dean, holds more than 288,000 volumes and is the only public medical library in Massachusetts and the regional medical library for New England.以首任院长命名的拉马尔·苏特图书馆藏书逾 28.8 万册，是全州唯一的公共医学图书馆，也是新英格兰地区的区域医学图书馆。
• That library is one of eight regional libraries of the National Library of Medicine and the state's leading source of biomedical material for inter-library loan.该馆是美国国家医学图书馆八个区域图书馆之一，也是全州馆际互借生物医学文献的主要来源。
• The ten-storey Aaron Lazare Medical Research Building, opened in 2001, stands next to the Massachusetts Biotechnology Research Park and houses more than 260 investigators.十层的拉扎尔医学研究大楼于 2001 年启用，毗邻马萨诸塞生物技术研究园，可容纳 260 多名研究人员。
• The extended campus includes the Brudnick Neuropsychiatric Research Institute, laboratories and offices in the Worcester biotechnology park, and sites in Shrewsbury and Auburn.扩展校区包括布鲁德尼克神经精神研究所、伍斯特生物技术园内的实验室与办公空间，以及什鲁斯伯里和奥本的教学点。
• It also includes the Eunice Kennedy Shriver Center in Waltham, the New England Newborn Screening Program, and MassBiologics laboratories in Jamaica Plain and Mattapan.扩展校区还包括沃尔瑟姆的尤妮斯·肯尼迪·施莱弗中心、新英格兰新生儿筛查项目，以及位于牙买加平原与马塔潘的马萨诸塞生物制品实验室。
• UMass Memorial Health Care employs about 13,000 people, including 1,500 physicians, and runs four community hospitals in Clinton, Fitchburg and Leominster, Milford and Southbridge.马萨诸塞大学纪念医疗集团雇有约 1.3 万名员工，其中医生 1500 人，并在克林顿、菲奇堡与莱明斯特、米尔福德和绍斯布里奇运营四所社区医院。
• The Worcester location places the school inside a dense cluster of hospitals, biotechnology firms and the state's only public medical library, within a compact New England city.伍斯特的选址使学校置身于医院、生物技术企业与全州唯一公共医学图书馆构成的密集集群之中，而这一切都在这座紧凑的新英格兰城市内。

Reputation

• UMass Chan sits in the 201-300 band of the 2026 Academic Ranking of World Universities, a placing carried by biomedical citation output rather than by undergraduate breadth.马萨诸塞大学陈医学院在 2026 年软科世界大学学术排名中处于第 201 至 300 名区间，这一位置由生物医学引用产出而非本科教育广度支撑。
• U.S. News ranks it 460th in the 2026-2027 global universities table, well below its standing in American primary-care and research medical school rankings.《美国新闻与世界报道》在 2026 至 2027 年度全球大学排名中把它列为第 460 位，远低于其在美国初级医疗与医学科研院校排名中的地位。
• The school does not appear in the 2027 Times Higher Education World University Rankings and did not enter the 2027 QS World University Rankings, both of which favour broad multi-faculty universities.该校未进入 2027 年泰晤士高等教育世界大学排名，也未进入 2027 年 QS 世界大学排名，这两个榜单都更青睐学科齐全的综合性大学。
• Its national reputation was built on primary care: the School of Medicine has consistently ranked in the top ten per cent of American medical schools in the U.S. News graduate guide.该校的全国声誉建立在初级医疗之上：其医学院长期位居《美国新闻与世界报道》研究生院指南所评全美医学院的前 10%。
• Two Nobel Prizes anchor its research reputation, the 2006 physiology or medicine award for RNA interference and the 2024 award for microRNA, both connected to the same RNA research community.两项诺贝尔奖支撑其科研声誉：2006 年因 RNA 干扰、2024 年因微小 RNA 分别获得生理学或医学奖，二者都出自同一个 RNA 研究群体。
• MassBiologics gives the school a capability few medical schools possess, the ability to manufacture licensed vaccines and biologics for public health use within a university campus.马萨诸塞生物制品所赋予该校多数医学院不具备的能力，即在大学校园内为公共卫生用途生产获许可的疫苗与生物制品。
• Research funding rose from two million dollars in 1977 to 322 million dollars in 2022, a growth curve that tracks its transition from a community medical school to a research medical centre.科研经费从 1977 年的 200 万美元增至 2022 年的 3.22 亿美元，这一增长曲线映照出它从社区医学院向研究型医学中心的转变。
• The RNA Therapeutics Institute and the Morningside graduate school have made the campus a recognised centre for RNA biology, with faculty in the National Academy of Sciences and the National Academy of Medicine.RNA 治疗研究所与 Morningside 研究生院使该校区成为公认的 RNA 生物学中心，其教员中有美国国家科学院与美国国家医学院院士。
• The 2025 decision to rescind all biomedical graduate admission offers after federal funding cuts damaged its reputation for stability and drew national attention to the dependence of medical research on federal grants.2025 年联邦经费削减后撤销全部生物医学研究生录取通知的决定，损害了其稳定性的声誉，也让全国注意到医学研究对联邦拨款的依赖。

Student life

• With roughly 165 students entering the MD programme each year, the medical school keeps a small-cohort culture in which students know their classmates and many faculty by name.医学院每年约招收 165 名医学博士生，维持着一种小规模班级文化，学生彼此熟识，也能叫出许多教师的名字。
• The primary-care mission shapes student culture, and more than half of each class has traditionally chosen residencies in family medicine, internal medicine, paediatrics and other primary fields.初级医疗使命塑造了学生文化，历史上每届都有超过一半的学生选择家庭医学、内科、儿科等全科方向的住院医师培训。
• Clinical students train at UMass Memorial Medical Center, a Level I trauma centre, and rotate through the system's four community hospitals in central Massachusetts.临床学生在一级创伤中心马萨诸塞大学纪念医疗中心受训，并在该系统位于马萨诸塞州中部的四所社区医院轮转。
• Graduate students in the biomedical sciences work in the laboratories of the Sherman Center and the Lazare building, sharing equipment and seminar programmes across departments.生物医学研究生在舍曼中心与拉扎尔大楼的实验室工作，跨系共用仪器与研讨课程。
• Nursing students on the advanced-practice tracks train alongside physicians and pharmacists in the same clinics, an interprofessional model built into the campus's three-school structure.高级执业方向的护理学生与医生、药师在同一批诊所中共同受训，这种跨专业模式内嵌于该校三所学院的架构之中。
• The Lamar Soutter Library serves as the campus study space and as a statewide biomedical information service, so students share their reading rooms with inter-library loan staff.拉马尔·苏特图书馆既是校园自习空间，也是全州生物医学信息服务枢纽，学生与馆际互借人员共用阅览室。
• Worcester's Route 9 corridor places restaurants, housing and the biotechnology park within a short distance of the teaching buildings, and Boston is reached by commuter rail.伍斯特的 9 号公路走廊使餐馆、住宅与生物技术园都在教学楼不远处，前往波士顿则可搭乘通勤铁路。
• With no undergraduate college on campus, student life revolves around the three graduate and professional schools and the hospital next door rather than around dormitories and intercollegiate sport.由于校园内没有本科学院，学生生活围绕三所研究生与专业学院以及隔壁的医院展开，而非围绕宿舍与校际体育。
• The 2025 rescission of graduate admission offers fell hardest on prospective PhD students, who had already accepted offers and were left without a cohort to join.2025 年撤销研究生录取通知的冲击主要落在已接受录取的博士新生身上，他们尚未入学便失去了原本要加入的班级。

Notable people

• Lamar Soutter, the founding dean of the School of Medicine, set the institution's community-oriented curriculum and is commemorated in the name of its library.医学院首任院长拉马尔·苏特确立了学校面向社区的课程方向，该校图书馆即以他的名字命名。
• Craig C. Mello, a Howard Hughes Medical Institute investigator at the school, discovered RNA interference with Andrew Fire in 1998 and shared the 2006 Nobel Prize in Physiology or Medicine.该校的霍华德·休斯医学研究所研究员克雷格·梅洛于 1998 年与安德鲁·法尔共同发现 RNA 干扰，并分享 2006 年诺贝尔生理学或医学奖。
• Victor Ambros, a co-founder of the RNA Therapeutics Institute, shared the 2024 Nobel Prize in Physiology or Medicine for discovering microRNA and its regulatory role.RNA 治疗研究所共同创办人维克托·安布罗斯因发现微小 RNA 及其调控作用，分享 2024 年诺贝尔生理学或医学奖。
• Phillip D. Zamore, a biochemist known for small-RNA discoveries, chairs the RNA Therapeutics Institute and has been elected to the National Academy of Sciences.以小 RNA 研究闻名的生物化学家菲利普·扎莫尔担任 RNA 治疗研究所所长，并当选美国国家科学院院士。
• Erik J. Sontheimer, a molecular biologist recognised for work on CRISPR-Cas systems, is vice-chair of the RNA Therapeutics Institute.因 CRISPR-Cas 系统研究而受认可的分子生物学家埃里克·松特海默担任 RNA 治疗研究所副所长。
• Anastasia Khvorova, an RNA biochemist, received the 2025 Else Kröner Fresenius Prize for Medical Research and works on chemically modified RNA drugs.RNA 生物化学家阿纳斯塔西娅·赫沃罗娃获得 2025 年埃尔泽·克勒纳·弗雷泽纽斯医学研究奖，研究方向为化学修饰的 RNA 药物。
• Job Dekker developed chromosome conformation capture, a method that revealed the three-dimensional organisation of chromosomes and changed how genomes are studied.乔布·德克尔开发了染色体构象捕获技术，该方法揭示了染色体的三维组织方式，改变了基因组研究的面貌。
• Katherine A. Fitzgerald, a molecular biologist and virologist, works on innate immune sensing and was a finalist for the 2011 Vilcek Prize.分子生物学家与病毒学家凯瑟琳·菲茨杰拉德研究先天免疫识别，曾入围 2011 年维尔切克奖决选。
• Shan Lu, a professor of medicine, led the school's DNA-based influenza vaccine programme in the 1990s and worked on an HIV vaccine that reached Phase I trials.医学教授卢山在 1990 年代主持该校的 DNA 流感疫苗项目，并参与研发进入Ⅰ期试验的艾滋病疫苗。
• Aaron Lazare, a psychiatrist who served as chancellor, is commemorated in the name of the ten-storey medical research building opened in 2001.精神科医生阿伦·拉扎尔曾担任校监，2001 年启用的十层医学研究大楼以他的名字命名。
• Chan Tseng-hsi, the Hong Kong property developer whose family gave 175 million dollars in 2021, is commemorated in the school's current name and in the names of its three schools.香港地产商陈曾熙的家族于 2021 年捐赠 1.75 亿美元，学校现名及其三所学院之名都以此纪念。