Toxicological Sciences

Toxicological Sciences is the official journal of the Society of Toxicology, published by Oxford University Press and covering the broad field of toxicology, with a 2025 impact factor of 5.2（Toxicological Sciences，简称 Toxicol. Sci.）是美国毒理学会的官方期刊，由牛津大学出版社出版，覆盖毒理学全领域，2025 年影响因子为 5.2。

Scope

• Publishes a broad spectrum of impactful research ranging from basic research to model development and application and decision making发表从基础研究到模型开发与应用及决策的广泛毒理学研究。
• Research areas include biomarkers and biotransformation, toxicokinetics and pharmacokinetics研究方向包括生物标志物以及生物转化、毒代动力学与药代动力学。
• Carcinogenesis, clinical and translational toxicology, and computational toxicology and databases致癌作用、临床与转化毒理、计算毒理与数据库。
• Developmental and reproductive toxicology, endocrine toxicology, environmental toxicology and exposure sciences发育与生殖毒理、内分泌毒理、环境毒理与暴露科学。
• Genetic and epigenetic toxicology, immunotoxicology, mixtures toxicology and nanotoxicology遗传与表观遗传毒理、免疫毒理、混合物毒理与纳米毒理。
• Molecular, biochemical and systems toxicology, neurotoxicology, organ-specific toxicology and regulatory science, risk assessment and decision making分子、生化与系统毒理、神经毒理、器官特异性毒理以及监管科学、风险评估与决策。
• Techniques span bioinformatics and computational biology, exposure science, mass spectrometry, molecular biology, population-based sciences, tissue and cell-based systems and whole-animal studies所用技术涵盖生物信息学与计算生物学、暴露科学、质谱、分子生物学、群体科学、组织与细胞系统以及整体动物研究。

History

• Its predecessor, Fundamental and Applied Toxicology, was founded in 1981 by the Society of Toxicology该刊前身为（Fundamental and Applied Toxicology），1981 年由美国毒理学会创办。^[1]
• The title was renamed Toxicological Sciences in January 1998 and began with volume 41, issue 11998 年 1 月更名为 Toxicological Sciences，以第 41 卷第 1 期起算。
• The first year under the new name was still published by Academic Press, and Oxford University Press took over from 1999现名首年 1998 年仍由 Academic Press 出版，自 1999 年起改由牛津大学出版社出版。^[2]
• Editors-in-chief have included the first, Curtis D. Klaassen, from 1998 to 2003, and Lois Lehman-McKeeman from 2003 to 2011历任主编包括首任 Curtis D. Klaassen（1998–2003）与 Lois Lehman-McKeeman（2003–2011）。
• The journal marked its twentieth anniversary in 20182018 年，该刊迎来创刊二十周年。^[3]
• Publication is hybrid open access, with no page charges for standard publication and an optional Oxford Open licence采用混合开放获取，常规发表不收版面费，作者可选择牛津开放获取许可。

Editors

• The editor-in-chief is Alison H. Harrill, in office since 1 July 2026, a regulatory toxicologist at Corteva Agriscience and formerly a senior science advisor at the United States Environmental Protection Agency现任主编 Alison H. Harrill，自 2026 年 7 月 1 日起就任，任职于科迪华农业科技，此前为美国环保署资深科学顾问。
• Her predecessor was Jeffrey M. Peters, professor of molecular toxicology and carcinogenesis at Pennsylvania State University前任主编为 Jeffrey M. Peters，宾夕法尼亚州立大学分子毒理与致癌作用教授。
• The deputy editor is Kristie Willett, head of the Department of BioMolecular Sciences at the University of Mississippi副主编为 Kristie Willett，密西西比大学生物分子科学系主任。
• The board comprises about 25 associate editors from countries including the United States, the United Kingdom, Sweden, France, Japan and China编委会设约二十五名副编辑，覆盖美国、英国、瑞典、法国、日本与中国等国。
• Review is single blind, with the editor and associate editor organising two or three referees who are asked to report within two weeks, and a decision is usually made within a further week采用单盲评审，由编辑与副编辑组织两至三名审稿人，审稿要求两周内完成，编辑决定通常再一周作出。
• Original research papers do not require a pre-submission enquiry, while review and forum papers are advised to submit a proposal to the editor first原创研究稿不要求投稿前咨询，综述与论坛类稿件则建议先向主编提交选题提案。