SLAS Discovery

SLAS Discovery is the open access journal of the Society for Laboratory Automation and Screening, published by Elsevier and addressed to those who build the tools and methods of drug discovery.《SLAS 发现》是实验室自动化与筛选学会的开放获取期刊，由 Elsevier 出版，面向药物发现工具与方法的构建者。

The title reports how researchers develop and use new approaches to furnish computational, chemical and biological tools for understanding and treating human disease.该刊报道研究者如何开发并运用新方法，提供用于理解与治疗人类疾病的计算、化学与生物学工具。

In the 2025 edition of the journal citation report it holds an impact factor of 3.3 and stands in the second quartile of biochemical research methods.在 2025 年版期刊引证报告中，该刊的影响因子为 3.3，在生化研究方法类目中列第二区。

Scope

• Work that enables and improves target validation is taken, and the journal is interested in methods that sharpen the case for a drug target.能够助力并改进靶点验证的工作受到收载，该刊对流化药物靶点论证的方法尤感兴趣。

• Novel methods for medium and high throughput screening form a central strand, and the journal invites papers that share or compare them.中等与高通量筛选的新方法是中心支线，该刊征求分享或比较这类方法的论文。

• Current drug discovery technologies are evaluated, and papers that put a method through its paces are admitted.对现行药物发现技术的评估也在收载之列，把某一方法彻底检验的论文同样被接纳。

• Novel research tools are welcomed, whether they are computational, chemical, biochemical or biological in character.新的研究工具受到欢迎，无论其属于计算、化学、生化还是生物学性质。

• Approaches that deepen knowledge and raise the chance of success in drug discovery are taken as an aim in themselves.能够加深认识并提高药物发现成功机会的思路，本身即被当作一个目标。

• Assay development appears among the areas named by the society, and the journal carries work on assays built for screening campaigns.分析方法开发见于学会点名的领域之中，该刊刊载为筛选活动而构建的分析工作。

• Biomarker discovery belongs to the scope, and studies that tie a marker to disease or to treatment response are admitted.生物标志物发现属于收稿范围，把标志物同疾病或治疗反应联系起来的研究也被接纳。

• Lead generation and lead optimisation are treated as core subjects, and the journal follows compounds from the first hit to a candidate.先导化合物的产生与优化被视为核心选题，该刊追踪化合物自首次命中到候选物的过程。

• Chemical biology is covered, and the journal takes work on small molecules used as probes rather than as drugs.化学生物学得到覆盖，该刊收载把小分子用作探针而非药物的研究。

• Informatics is included among the subjects, and work on data handling, machine learning and computational prediction has appeared in its pages.信息学也在选题之中，关于数据处理、机器学习与计算预测的工作曾见于该刊。

• Virtual screening sits alongside the laboratory methods, and the journal considers studies that rank large compound collections in silico.虚拟筛选与实验方法并列，该刊考虑在计算机上对大型化合物集合排序的研究。

• The journal makes room for short communications beside full research papers, so that a single method or a single tool can be reported on its own.该刊在完整研究论文之外为短篇通讯留出位置，使单一方法或单一工具得以单独报告。

• Joining academia and industry is part of the design of the journal, and it draws authors and readers from both.连接学术界与产业界是该刊设计的一部分，作者与读者都来自这两个方面。

• The journal runs alongside SLAS Technology, and the two titles share the same society, publisher and editorial outlook.该刊与 SLAS Technology 并行，两份刊物共享同一学会、同一出版方与同一编辑取向。

• Cancer research is a recurring subject, and tools for probing fibrosis in tumours were among the topics of a recent volume.癌症研究是反复出现的题目，探测肿瘤纤维化的工具是某一近卷的选题之一。

• Screening platforms lie at the heart of the journal, and work on assay miniaturisation and on automation has appeared in its pages.筛选平台是该刊的核心，关于分析微型化与自动化的工作曾见于其页面。

• Contributions on artificial intelligence and machine learning are admitted where they bear on compound selection or on assay design.关于人工智能与机器学习的投稿在其关联化合物选择或分析方法设计时被接纳。

• The journal accepts submissions from both industry and academia, and it expects authors to report methods in enough detail for others to repeat them.该刊同时接受产业界与学术界的来稿，并要求作者把方法写得足够详尽，以便他人重现。

• News of the society appears alongside the science, and notices of webinars, awards and reviewer recognition are carried with the journal.学会的消息与科学内容并列，网络研讨、奖项与审稿人表彰的公告随刊物一同发布。

History

• The journal traces its origin to 1996, when it was founded under the title Journal of Biomolecular Screening.该刊的源头可上溯到 1996 年，当时以 Journal of Biomolecular Screening 为名创办。

• From the first issue of 2017 the title became SLAS Discovery, and the volume numbering carried straight on from the earlier name into volume 22.自 2017 年的首期起，刊名改为 SLAS Discovery，卷号自旧名直接延续到第 22 卷。

• The earlier years were published from Thousand Oaks in California by SAGE, which hosted the content from 1996 until December 2021.早年各卷由 SAGE 在加利福尼亚州千橡市出版，该社自 1996 年起托管内容直至 2021 年 12 月。

• From 2022 the title has been published by Elsevier, and submissions now go through the new publisher's platform.自 2022 年起，该刊由 Elsevier 出版，投稿也转到新出版方的平台。

• The journal is now fully open access, and every article is free to read, download and redistribute as soon as it appears.该刊如今是完全开放获取的，每篇文章一经刊出即可自由阅读、下载与再分发。

• Publication runs to ten issues a year, and the journal is issued online only, with no printed edition.该刊每年出版十期，且仅在线上发行，没有印刷版。

• The print number is 2472-5552 and the electronic number is 2472-5560, and the title is the work of the Society for Laboratory Automation and Screening.印刷版编号为 2472-5552，电子版编号为 2472-5560，该刊是实验室自动化与筛选学会的出版物。

• MEDLINE and PubMed have indexed the title from volume 22, number 1 in 2017, and it also appears in the analytical chemistry services.MEDLINE 与 PubMed 自 2017 年第 22 卷第 1 期起收录该刊，它也见于分析化学类检索服务。

• The impact indicator has moved from 2.918 and 3.341 to 2.7 and 2.7, and it stood at 3.3 in the 2025 edition.影响因子从 2.918 与 3.341 变为 2.7 与 2.7，在 2025 年版为 3.3。

• Open access was adopted to widen reach, and the society has said that it expects the change to raise citations and visibility for its authors.转向开放获取意在扩大触达，学会曾表示预期这一改变将提高作者的被引与可见度。

• The journal marks its work against the sibling title SLAS Technology, and the two are run together by the society and its publisher.该刊与姊妹刊 SLAS Technology 相互参照，两者由学会及其出版方共同运营。

• Open access was adopted so that the work the society publishes could reach readers without a subscription.转向开放获取，是为了让学会发表的工作能在无需订阅的情况下抵达读者。

Editors

• The editor-in-chief is Robert M. Campbell, a scientist at Eli Lilly and Company.主编是（Robert M. Campbell），礼来公司的科学家。

• Associate editors work with the editor-in-chief, and Timothy Spicer is one of them.若干副编辑与主编共事，（Timothy Spicer）即为其中一位。

• The editorial board and the reviewer community together draw on the labour of close to a thousand volunteers each year.编委会与审稿人群体加起来，每年投入的志愿工作约有近千人。

• The journal is double held to peer review, and every paper is sent out to independent referees before it can be accepted.该刊严格实行同行评审，每篇论文在获录用前都送交独立审稿人。

• Handling editors look for referees beyond their usual networks, so that a manuscript is not judged by the same small circle every time.处理稿件的编辑会在惯常圈子之外寻找审稿人，使稿件不致每次都由同一小群人评判。

• Articles are published under a Creative Commons attribution licence, and readers may reuse the material with credit to the authors.文章以 Creative Commons 署名许可发布，读者可在注明作者的前提下再利用其材料。

• A charge is levied on accepted papers to cover the cost of open access, and the society publishes details of the arrangement.为覆盖开放获取的成本，录用的论文须缴纳费用，学会公布了相关安排的细节。

• Special issues are organised around defined problems, and a joint challenge on compound solubility was among the recent ones.专刊围绕明确的问题组织，其中一期针对化合物溶解度的联合挑战赛即为近例。

• Manuscripts are submitted online and the journal states its editorial scope in full, so that authors can judge whether a paper fits.稿件在线投递，该刊完整公布其编辑范围，以便作者判断论文是否契合。

• The society runs webinars and reviewer recognition alongside the journal, drawing in researchers from Asia, Europe and the Americas.学会在刊物之外还举办网络研讨与审稿人表彰，吸引来自亚洲、欧洲与美洲的研究者。