Pflügers Archiv - European Journal of Physiology

本刊是 1868 年由德国生理学家 Eduard Pflüger 创办的同行评审期刊，现由 Springer 出版，是德国生理学会的会刊。

刊物覆盖人体与动物生理学的全部分支，从离子通道与膜转运一直到器官系统的整合调节，并延伸到生理过程失常所致的疾病机制。

2025 年影响因子为 3.2，五年影响因子为 4.3，在生理学 89 种期刊中列第 27 位，处于第二四分位。

Scope

• Pflügers Archiv publishes work on the physiology of humans and animals, from molecular transport to organ-level integration.本刊发表人类与动物生理学的研究，范围从分子转运延伸到器官层面的整合。
• Ion channels, transporters and pumps form the historical core of the journal's content.离子通道、转运体与离子泵构成本刊历史最悠久的内容核心。
• Membrane excitability, synaptic transmission and the properties of sensory neurons are regular subjects.膜兴奋性、突触传递与感觉神经元特性是常见的选题。
• Renal physiology receives sustained attention, including tubular transport and the regulation of salt and water balance.肾脏生理受到持续关注，包括小管转运以及盐水平衡的调节。
• Cardiovascular work covers excitation-contraction coupling, vascular smooth muscle and the control of blood pressure.心血管方面的工作涵盖兴奋收缩耦联、血管平滑肌与血压调控。
• Respiratory physiology, acid-base regulation and the control of breathing are within the journal's remit.呼吸生理、酸碱调节与呼吸运动的控制也在刊物范围之内。
• Gastrointestinal, hepatic and pancreatic physiology appears alongside metabolic and endocrine studies.胃肠、肝脏与胰腺生理与代谢和内分泌研究一并出现。
• Skeletal, cardiac and smooth muscle physiology is treated at the level of sarcomere, fibre and whole muscle.骨骼肌、心肌与平滑肌生理在肌节、纤维与整块肌肉三个层面得到讨论。
• Neuroendocrine function and the hypothalamic-pituitary axis are examined in health and disease.神经内分泌功能与下丘脑垂体轴在健康与疾病状态下均被考察。
• Comparative physiology and the adaptation of animals to extreme environments retain a place in the journal.比较生理学以及动物对极端环境的适应在刊物中仍占一席之地。
• Channelopathies and defects in transporter function connect molecular findings to clinical phenotypes.通道病与转运体功能缺陷把分子层面的发现与临床表型联系起来。
• Genetic models, electrophysiology, live imaging and omics approaches are all represented among published methods.遗传模型、电生理、活体成像与组学方法在发表的方法学中均有体现。
• Reviews and mini-reviews summarise fast-moving areas for a readership that spans basic and clinical physiology.综述与小型综述为横跨基础与临床生理学的读者梳理发展迅速的领域。
• Methodological papers that establish a new preparation or measurement are considered when they open fresh questions.能够开辟新问题的技术论文，若建立了新的标本制备或测量手段，也会被考虑。
• The journal welcomes work that links physiological mechanism to the pathogenesis of human disease.刊物欢迎把生理机制与人类疾病发病机制相联系的稿件。
• Studies on ageing, exercise and environmental stress are read as extensions of integrative physiology.衰老、运动与环境应激的研究被视作整合生理学的延伸。
• Interactions between the nervous system and visceral organs are studied through autonomic reflex pathways.神经系统与内脏器官的相互作用通过自主神经反射通路加以研究。
• Temperature regulation, hibernation and the physiology of hibernators have a long tradition in the journal.体温调节、冬眠以及冬眠动物的生理学在本刊有悠久的传统。
• Epithelial barrier function and the transport of electrolytes across tight junctions are recurring topics.上皮屏障功能与电解质跨紧密连接转运是反复出现的主题。
• Hypoxia, oxidative stress and mitochondrial energetics are examined at the level of the whole organism.缺氧、氧化应激与线粒体能量学在整体动物层面得到考察。
• Studies that combine a genetic manipulation with a clear physiological readout are especially welcome.把遗传操作与明确的生理读出结合起来的论文尤其受到欢迎。

History

• The journal was founded in 1868 by Eduard Pflüger as the Archiv für die gesamte Physiologie des Menschen und der Thiere.刊物于 1868 年由 Eduard Pflüger 创办，最初以德文刊名《人类与动物生理学全录》出版。
• Pflüger, a professor in Bonn, edited the journal until his death in 1910.Pflüger 是波恩大学的教授，主持刊物直到 1910 年去世。
• Successive volumes carried the journal through the first half of the twentieth century under the same title.此后各卷以同一刊名把刊物带入二十世纪上半叶。
• Publication was suspended in 1945 and 1946 in the aftermath of the Second World War.第二次世界大战结束后，刊物在 1945 年与 1946 年一度停刊。
• With volume 302 in 1968 the journal took its present name, Pflügers Archiv - European Journal of Physiology.1968 年出版第 302 卷时，刊物改用现名，并加上欧洲生理学杂志的副题。
• Articles were written in German until 1968, after which several European languages were accepted for a period.1968 年以前文章以德文发表，此后一段时间内接受多种欧洲语言。
• English became the sole language of publication in May 1997.1997 年 5 月起，英文成为唯一的发表语言。
• The journal is the official organ of the German Physiological Society and reports on the society's activities.刊物是德国生理学会的正式会刊，并报道学会的活动。
• Springer publishes the journal from Heidelberg, and the editorial office handles several hundred submissions each year.刊物由 Springer 在德国海德堡出版，编辑部每年处理数百篇投稿。
• The journal marked its sesquicentenary in 2018, having appeared without interruption apart from the postwar pause.除战后短暂停刊外刊物连续出版，2018 年迎来创刊一百五十周年。^[1]
• Impact factors over the past five years were 3.657 in 2021, 4.458 in 2022, 2.9 in 2023 and 2024, and 3.2 in 2025.近五年影响因子依次为 2021 年的 3.657、2022 年的 4.458、2023 年与 2024 年的 2.9 以及 2025 年的 3.2。
• In 2025 the journal recorded about 1.4 million downloads and a median time to first decision of four days.2025 年刊物全文下载量约 140 万次，初审中位时间为四天。
• Publication is hybrid, with subscription content and an Open Choice option for authors who wish to make articles freely available.刊物采用混合出版模式，既有订阅内容，也为希望免费开放文章的作者提供开放获取选项。
• The journal is indexed in Science Citation Index Expanded and in the usual biomedical abstracting services.刊物被科学引文索引扩展版以及通行的生物医学文摘服务收录。
• Its archive now runs to more than three hundred volumes and is consulted for nineteenth-century physiological work.刊物现存卷册已超过三百卷，十九世纪的生理学工作仍可在此查阅。

Editors

• Carsten A. Wagner of the University of Zurich is editor-in-chief and works on renal tubular transport.苏黎世大学的 Carsten A. Wagner 担任主编，研究方向为肾小管转运。
• Matthew Bailey of the University of Edinburgh handles renal and epithelial physiology.爱丁堡大学的 Matthew Bailey 负责肾脏与上皮生理方面的稿件。
• Emilio Carbone of the University of Turin covers ion channels and cellular neurophysiology.都灵大学的 Emilio Carbone 负责离子通道与细胞神经生理学。
• Andreas Draguhn of Heidelberg University handles synaptic physiology and network activity.海德堡大学的 Andreas Draguhn 负责突触生理与网络活动。
• Joachim Fandrey of the University of Duisburg-Essen works on oxygen sensing and erythropoiesis.杜伊斯堡埃森大学的 Joachim Fandrey 研究氧感受与红细胞生成。
• Ingrid Fleming of Goethe University Frankfurt covers vascular biology and endothelial signalling.法兰克福歌德大学的 Ingrid Fleming 负责血管生物学与内皮信号。
• Stefan Gründer of RWTH Aachen University handles sensory and epithelial ion channels.亚琛工业大学的 Stefan Gründer 负责感觉与上皮离子通道。
• Luis Sobrevia of the Pontificia Universidad Católica de Chile works on placental and vascular transport.智利天主教大学的 Luis Sobrevia 研究胎盘与血管转运。
• Nuša Likar serves as social media editor and coordinates the journal's online presence.Nuša Likar 担任社交媒体编辑，负责刊物的线上呈现。
• The editorial board numbers about seventy members drawn from Germany, the United States, Japan, Korea, China and elsewhere.编委会约有七十名成员，来自德国、美国、日本、韩国、中国等地。
• Board members are grouped by physiological system so that each submission reaches a specialist quickly.编委按生理系统分组，使每篇稿件都能迅速送到对口的专家手中。
• Research articles are sent to independent external referees chosen by the handling editor.研究论文由负责编辑挑选独立的外部专家评审。
• Reviews and commentaries are commissioned, and authors are asked to enquire before submitting one.综述与评论采取约稿制，作者投稿前需先与编辑部联系。
• Mini-reviews are limited to 2,500 words, two or three figures and no more than twenty references.小型综述限制在 2500 词、两三幅图与不超过二十条参考文献。
• The editor-in-chief commissions mini-reviews on topics that the board considers timely.小型综述由主编就编委会认为适时的主题发出邀请。
• Editorial decisions are communicated with the referees' comments, and revised manuscripts return to the original reviewers.编辑决定连同审稿意见一并传达，修回稿件送回原审稿人复核。