Neurology: Genetics

Neurology: Genetics is an online open access journal of the American Academy of Neurology, published by Wolters Kluwer, that began in 2015. It publishes work on the role of genetic and epigenetic variation in the nervous system, and its 2025 impact factor is 3.3.《神经遗传学》是美国神经病学学会的在线开放获取期刊，由 Wolters Kluwer 出版，2015 年创办。该刊发表遗传与表观遗传变异在神经系统中作用的研究，2025 年影响因子为 3.3。

Scope

• The journal is published for neurologists, and it takes original contributions that bear on the nervous system.该刊为神经科医师出版，接收有关神经系统的重要原创论文。

• The role of genetic variation in disease is studied, so a paper may link a variant to a condition.遗传变异在疾病中的作用受到研究，因此论文可以把一种变异与某一疾病联系起来。

• Epigenetic variation is named beside it, since a mark on the genome can change what a cell does.表观遗传变异与之并列列出，因为基因组上的标记可以改变细胞的行为。

• Biological traits of the central nervous system are covered, and a study may follow a trait through a family.中枢神经系统的生物学性状也在覆盖之列，研究可以在一个家系中追踪某一性状。

• The peripheral nervous system is named as well, so a neuropathy may be examined at the level of the gene.周围神经系统也被列出，因此一种神经病可以在基因层面受到检视。

• Rare genetic variation is taken, and a paper may report a variant seen in only a few families.罕见遗传变异会被接收，论文可以报告仅见于少数家系的变异。

• Common genetic variation is studied too, since a frequent variant may shift a risk across a whole population.常见遗传变异同样受到研究，因为一个高频变异可以在整个人群中移动风险。

• Genotype and phenotype are correlated in many of its papers, because the link between the two is the point of the work.该刊许多论文把基因型与表型相关联，因为两者之间的联系正是研究的关键。

• Outlier phenotypes that follow from a mutation are taken, since a striking case often teaches more than a typical one.由突变导致的离群表型会被接收，因为一个突出病例常比典型病例更能教人。

• Mutations in genes already known to cause disease are examined, and a paper may widen the range of what such a gene explains.已知致病基因中的突变受到检视，论文可以拓宽这类基因所解释的范围。

• Variants with a putative link to a disease are reported, even when the evidence is early, so long as the account is clear about what is known.与疾病有推定联系的变异会被报道，即便证据尚早，只要记述清楚说明已知的部分。

• The journal is clinical and translational, so a finding is expected to bear on the care of a patient.该刊是临床与转化的，因此一项发现被期望关涉患者的照护。

• Original articles form the bulk of its pages, and editorials and reviews appear beside them.原创论文构成其版面的大部分，社论与综述与之并列出现。

• The scope was widened after the journal had been running for several years, so the range of papers it takes is now broader than at the start.在该刊运行数年后其范围被拓宽，因此它所接收论文的跨度比创办时更广。

• A paper may report a variant found in a single family, setting out what the family shares and what makes its case unusual.论文可以报告仅在单个家系中发现的变异，说明该家系共有什么以及使其病例有何不寻常。

• Work on the genetics of a movement disorder is taken, since a tremor or a dystonia often has a heritable basis.运动障碍遗传学方面的工作会被接收，因为震颤或肌张力障碍常有其可遗传的基础。

• The journal covers the genetics of epilepsy, and a study may trace a seizure disorder through several generations.该刊覆盖癫痫的遗传学，研究可以追踪一种发作性疾患跨越数代。

• Work on the muscular dystrophies appears, since the gene behind each form is now known in many cases.肌营养不良症方面的工作出现于该刊，因为如今许多类型的致病基因已知。

• A paper may study a neuropathy that runs in a family, comparing the findings across the members who took part.论文可以研究在某一家系中遗传的神经病，比较参与成员之间的发现。

• The journal takes work on the genetics of a brain malformation, since the shape of the brain often points to a gene.该刊接收脑畸形遗传学的工作，因为脑的形态常指向某一基因。

• Work on repeat expansions is covered, since a repeated stretch of DNA can lengthen across generations.重复扩增方面的工作也在覆盖之列，因为一段重复的基因序列可以跨代延长。

• The journal takes studies that use sequencing to find the cause of an undiagnosed neurological condition, which is one of its most common kinds of paper.该刊接收用测序寻找未确诊神经系统疾病病因的研究，这是它最常见的一类论文之一。

• A paper may report the genotype of a patient beside the course of the disease, so a reader can judge the link.论文可以把患者的基因型与病程并列报告，使读者能判断其中的联系。

• The journal takes work on the genetics of a nerve tumour, since an inherited tendency can raise the risk for a family.该刊接收神经肿瘤遗传学的工作，因为一种可遗传的倾向会提高一个家系的风险。

• A paper may study a disorder of the neuromuscular junction, where the signal between nerve and muscle fails.论文可以研究神经肌肉接头的一种疾患，在那里神经与肌肉之间的信号失效。

• Work on the genetics of a leukodystrophy is covered, since these conditions often run in families.脑白质营养不良的遗传学方面的工作也在覆盖之列，因为这些疾患常在家族中遗传。

• The journal takes work on the genetics of a headache disorder, since a familial pattern is common in that group.该刊接收头痛疾患遗传学的工作，因为家族性格局在该类群中很常见。

• A paper may report the yield of a genetic test in a clinic, showing how often it settles a diagnosis.论文可以报告某项基因检测在门诊中的产出率，显示它在多大比例上敲定诊断。

• Work on the genetics of a stroke in a young patient is taken, since an uncommon cause may lie in a gene.年轻患者卒中的遗传学方面的工作会被接收，因为不常见的原因可能在于某一基因。

• The journal covers the genetics of a cognitive disorder, and a study may compare two families that carry the same variant.该刊覆盖认知障碍的遗传学，研究可以比较携带同一变异的两个家系。

• A paper may set out how a cohort was gathered for a genetic study, and the editors ask that this be described plainly.论文可以说明一个队列是如何为遗传研究而征集的，编辑要求把这一点清楚写出。

• Work on the interaction between two genes is taken, since a disease may need a change in each before it appears.两个基因之间相互作用的工作会被接收，因为疾病在显现前可能需要两者各有一处改变。

• The journal covers the reading of a variant of uncertain significance, a problem that faces every clinic in this field.该刊覆盖意义未明变异的解读，这是该领域每一家门诊都会面对的问题。

• A paper may report a family in which a variant and a disease do not travel together, which is itself a useful finding.论文可以报告一个变异与疾病并不共同传递的家系，这本身就是一个有用的发现。

History

• The journal was launched in 2015, when the academy began an online title for the field.该刊于 2015 年创办，当时学会为该领域开办了一份在线刊物。

• It is an official journal of the American Academy of Neurology.该刊是美国神经病学学会的一份官方期刊。

• It appears in electronic form only, and it carries the number 2376-7839.该刊仅以电子形式出现，其刊号为 2376-7839。

• Six issues appear in a year, so the title is bimonthly.该刊每年出版六期，因此为双月刊。

• Every article is free to read on the day it appears, since the journal is open access.每篇文章在发表当天即可免费阅读，因为该刊是开放获取的。

• Its impact factor was 3.485 for 2021 and 3.3 for 2025, with a five-year figure of 3.6.其影响因子 2021 年为 3.485，2025 年为 3.3，五年影响因子为 3.6。

• It is indexed in the Science Citation Index Expanded and in Scopus.该刊被科学引文索引扩展版与 Scopus 收录。

• The title belongs to a family of journals that share a name, and their policies are set together.该刊属于一个共用名称的期刊家族，它们的政策共同确定。

• A statement on the use of artificial intelligence sets out how such tools may be used in a manuscript.一份人工智能使用声明说明了此类工具在稿件中可以如何使用。

• Every article is peer reviewed before it appears, and the record of each paper is kept by the office.每篇文章在发表前都经同行评审，每篇论文的记录由编辑部保存。

Editors

• (Peter B. Kang) is the editor of the journal.（Peter B. Kang）是该刊编辑。

• He is a neurologist with an interest in the genetics of the nervous system.他是一位关注神经系统遗传学的神经科医师。

• The journal is edited for the academy, and the academy appoints its editor.该刊为学会编辑，编辑由学会任命。

• An editorial board of neurologists and geneticists governs the review of submissions.一个由神经科医师与遗传学家组成的编委会主持来稿的评审。

• Each manuscript is sent to specialists who work on the condition it addresses.每篇稿件都被送给研究其所涉疾病的专家。

• The editors receive the reports and take the decision on a paper.编辑收到报告后就论文作出决定。

• The journal office answers queries about submission and follows each paper.该刊办公室答复关于投稿的询问并跟踪每篇论文。

• The board covers the branches of the field, so a paper is read by someone who knows its material.编委会覆盖该领域的各分支，因此论文由了解其材料的人审读。

• The editors state that a study is judged on what it adds to the care of a patient with a neurological disease.编辑声明一项研究据其对神经系统疾病患者照护的贡献来评判。