Journal of Clinical Research in Pediatric Endocrinology

Journal of Clinical Research in Pediatric Endocrinology is an English language journal confined to the hormonal and metabolic diseases of infancy, childhood and adolescence, with diabetes mellitus handled as a field beside endocrinology rather than inside it.《儿科内分泌临床研究杂志》是一份只覆盖婴幼儿，儿童与青少年激素及代谢疾病的英语期刊，糖尿病在其中被当作与内分泌并列的独立领域处理。

It is the official publication of the Turkish Society for Pediatric Endocrinology and Diabetes and is produced in Istanbul by Galenos Publishing House, which also hosts the online submission system the title uses.该刊是土耳其儿童内分泌与糖尿病学会（Turkish Society for Pediatric Endocrinology and Diabetes）的官方出版物，由伊斯坦布尔的 Galenos Publishing House 承制，在线投稿系统亦由该出版方托管。

Four numbered issues appear each calendar year, dated March, June, September and December, and every article is free to read from the moment of online release under a Creative Commons licence that rules out commercial reuse and adaptations.每年出 4 期，分别标注 3 月，6 月，9 月与 12 月，论文自在线发布起即可免费阅读，所采知识共享许可排除商业使用与改编。

Clarivate reported a 2025 impact factor of 1.9 with a five-year figure of 2.0, and the Scopus record carries a CiteScore of 3.1 beside it.Clarivate 公布的 2025 年影响因子为 1.9，5 年影响因子为 2.0，Scopus 收录的 CiteScore 为 3.1。

Scope

• The declared purpose is clinical and translational work capable of altering bedside decisions, and the editorial page states a preference for findings with immediate bearing on paediatric practice.办刊目的写明为可改变床边决策的临床与转化研究，编辑页表明更看重对儿科实践有直接影响的发现。
• Growth and its disorders take the largest single share of the table of contents, from growth hormone deficiency testing and recombinant therapy to the once-weekly preparation (somatrogon) and models that predict final height.生长及其障碍占目录的最大单一份额，涉及生长激素缺乏的激发试验与重组治疗，每周一次的长效制剂（somatrogon），以及成年身高预测模型。
• Puberty is followed in both directions, central precocious puberty under gonadotropin releasing hormone analogues on one side and hypogonadism, gonadal dysgenesis and absent puberty on the other.青春期议题双向展开，一侧是用促性腺激素释放激素类似物处理的中枢性性早熟，另一侧是性腺功能减退，性腺发育不全与青春期缺如。
• Diabetes occupies standing space, with continuous glucose monitoring metrics, pump and hybrid closed loop practice, ketoacidosis and its cerebral oedema risk, microvascular complications beginning in childhood, and monogenic forms such as GCK-MODY.糖尿病在刊内常驻，内容含持续血糖监测指标，泵与混合闭环治疗实践，酮症酸中毒及其脑水肿风险，自儿童期起的微血管并发症，以及 GCK-MODY 一类单基因类型。
• Thyroid disease recurs across the volumes, spanning screened congenital hypothyroidism, subclinical forms carrying TSHR variants, autoimmune thyroiditis, adolescent nodules, Graves disease and resistance to thyroid hormone.儿童甲状腺疾病在各卷反复出现，包括经筛查发现的先天性甲状腺功能减退，伴 TSHR 变异的亚临床型，自身免疫性甲状腺炎，青少年甲状腺结节，Graves 病与甲状腺激素抵抗。
• Adrenal and steroid biosynthesis disorders are published regularly, among them the several enzyme forms of congenital adrenal hyperplasia, ACTH-independent Cushing syndrome, familial glucocorticoid deficiency and primary adrenal insufficiency inside rare syndromes.肾上腺与类固醇合成障碍刊出频繁，见于先天性肾上腺皮质增生的多种酶缺陷型，促肾上腺皮质激素非依赖性库欣综合征，家族性糖皮质激素缺乏，以及罕见综合征内的原发性肾上腺皮质功能减退。
• Disorders of sex development receive sustained space, including 46 XY and 46 XX presentations, aromatase and 17 alpha hydroxylase deficiency, androgen insensitivity, and the psychiatric follow up of adolescents with gender incongruence.性发育异常获得持续版面，涉及 46 XY 与 46 XX 核型表现，芳香化酶缺陷与 17 α 羟化酶缺陷，雄激素不敏感，以及性别不安青少年的精神科随访。
• Hypoglycaemia of the newborn is treated as a specialty of its own, reported through ABCC8 and AKT2 variants, diazoxide response, and long term results of somatostatin analogue therapy in congenital hyperinsulinism.新生儿与婴儿低血糖按独立专科处理，报道线索包括 ABCC8 与 AKT2 变异，二氮嗪疗效，以及先天性高胰岛素血症使用生长抑素类似物的长期结果。
• Bone and mineral disease covers genetic and nutritional causes alike, from hypophosphataemic rickets and the many forms of osteogenesis imperfecta to pseudohypoparathyroidism, vitamin D deficiency and the skeletal effect of chronic illness.骨与矿物质疾病兼顾遗传性与营养性病因，从低血磷性佝偻病与成骨不全的多种类型，到假性甲状旁腺功能减退，维生素 D 缺乏与慢性病对骨骼的影响。
• Adiposity and lipid disease draw a steady flow of submissions, among them early childhood obesity with familial clustering, steatotic liver disease, severe hypertriglyceridaemia from APOA5 variants, and leptin pathway defects treated with the drug (setmelanotide).肥胖与血脂异常来稿不断，涵盖有家族聚集的幼儿期肥胖，脂肪性肝病，APOA5 变异所致的重度甘油三酯升高，以及以药物（setmelanotide）治疗的瘦素通路单基因缺陷。
• Pituitary and hypothalamic disease appears in acquired and congenital guises, with craniopharyngioma related hypothalamic syndrome, isolated ACTH deficiency from TBX19 variants, multiple pituitary hormone defects and prolactinoma.垂体与下丘脑疾病兼收获得性与先天性两类，刊出过颅咽管瘤相关下丘脑综合征，TBX19 变异导致的孤立性 ACTH 缺乏，多种垂体激素缺陷与泌乳素瘤。
• Method and measurement are subjects in their own right, with auxological reference curves, the LMS parameters behind them, urinary biomarkers, nailfold capillaroscopy, and the timing of cortisol sampling in the low dose Synacthen test.方法与测量本身即是讨论对象，涉及生长参考曲线与其背后的 LMS 参数，尿液生物标志物，甲褶毛细血管镜，以及小剂量促肾上腺皮质激素兴奋试验的皮质醇取样节点。
• Original articles, reviews, short communications, brief reports, letters to the editor, editorials and case reports that add a novel insight make up the citable content, and a graphical abstract is expected with each paper.可引内容由原创论著，综述，简短报告，读者来信与社论构成，病例报道须提供新见解，作者投稿时需附图形摘要。

History

• The journal started in 2008 as the periodic publication of the Turkish Society for Pediatric Endocrinology and Diabetes, and the society's own record gives January 2008 as the foundation date.该刊 2008 年作为土耳其儿童内分泌与糖尿病学会的定期出版物起步，学会一侧的记载把创办时间定为 2008 年 1 月。
• The National Library of Medicine opens its catalogue record at volume one number one, dated September 2008, eight months later than the founding month printed on the journal site.美国国家医学图书馆目录的收录起点是第 1 卷第 1 期，标注 2008 年 9 月，比期刊网站所载创办时间晚 8 个月。
• Volume one ran across two calendar years, carrying two issues in 2008 and four more in 2009 with a supplement attached, before the present pattern of one volume per year took hold from volume two in 2010, and the archive now lists 83 recorded parts up to the September 2026 issue of volume eighteen, whose pagination runs past page 400.第 1 卷横跨两个自然年，2008 年出 2 期，2009 年续出 4 期并附增刊 1 份，自 2010 年第 2 卷起才固定为每年一卷，网站存档至今共列 83 个期次条目，最新一期是 2026 年 9 月的第 18 卷第 3 期，同一卷年内页码已越过 400 页。
• Much of the opening material was commissioned narrative review, the first issue collecting papers on the genetics of growth hormone deficiency, the physiology of growth hormone secretion and the epidemiology of childhood obesity创刊内容多为约稿综述，首期即收有生长激素缺乏的遗传学，生长激素分泌的生理学与儿童肥胖流行病学等篇目。^[1]
• Galenos Publishing House, based in the Fatih district of Istanbul, runs production and the web platform while the society keeps ownership of the title, and the library imprint carries the society and the publisher as separate statements for the same journal.出版与网络平台由伊斯坦布尔 Fatih 区的 Galenos Publishing House 运营，刊名所有权留在学会，图书馆出版项为同一刊名分别登记学会与出版社两条归属。
• Early articles were registered under the DOI prefix 10.4008, while later content is deposited under 10.4274, the prefix held by the publisher, with identifiers that embed the journal abbreviation and the year of acceptance.早期论文以 10.4008 前缀登记 DOI，后续内容改在出版方持有的 10.4274 前缀下提交，标识号内嵌入刊名缩写与录用年份。
• MEDLINE coverage begins with the first issue and is marked as full indexing rather than selected citations, and PubMed Central carries the same range from 2008 forward.MEDLINE 收录自创刊第一期起，标注为全量标引而非选择性摘录，PubMed Central 的覆盖区间同为 2008 年至今。
• The journal's own list of services adds Scopus, Embase, the DOAJ entry, the Turkish TR Dizin and Türk Medline files, the Türkiye citation index, EBSCO, Gale, ProQuest, CNKI, Reaxys, Engineering Village, the British Library, Idealonline, J-Gate and Sudoc.期刊自列的收录与摘要名录还含 Scopus，Embase，开放获取期刊目录，土耳其的 TR Dizin 与 Türk Medline，Türkiye 引文索引，EBSCO，Gale，ProQuest，CNKI，Reaxys，Engineering Village，大英图书馆，Idealonline，J-Gate 与 Sudoc。
• Free access has been the model since the first volume, the DOAJ record dating that start to 2008, while the licence adopted is CC BY-NC-ND 4.0 and copyright passes to the journal once a manuscript is accepted.免费阅读模式自第 1 卷即已确立，开放获取期刊目录记录的起点为 2008 年，采行许可为 CC BY-NC-ND 4.0，著作权在稿件录用后转归期刊。
• A charge on accepted papers was introduced on 1 January 2025 at 350 US dollars for original articles, 275 for case reports and 500 for reviews submitted without an invitation, with nothing asked during submission or review.自 2025 年 1 月 1 日起对录用论文收费，原创论著 350 美元，病例报道 275 美元，非约稿综述 500 美元，投稿与评审环节不收费。
• Reported impact factors read 2.016 for 2022, 1.5 for 2023 and 2024, then 1.9 for 2025, when the citation report counted 56 citable research items, 1828 cumulative citations, a cited half life of 7.8 years and a Journal Citation Indicator of 0.65.影响因子在 2022 年记为 2.016，2023 年与 2024 年同为 1.5，2025 年升至 1.9，同年引文报告计有 56 篇可引研究论文，累计被引 1828 次，被引半衰期 7.8 年，Journal Citation Indicator 为 0.65。
• The 2025 edition places the title in the second quartile of paediatrics at rank 85 of 190 journals and in the fourth quartile of endocrinology and metabolism at rank 154 of 198, while Crossref holds 232 current records behind 1025 backfile ones under these two ISSNs.2025 年版别将其列在儿科学第二分区，190 种期刊中排第 85，内分泌学与代谢学第四分区，198 种中排第 154，Crossref 在两个 ISSN 下存有当期记录 232 条与过刊记录 1025 条。
• The wording of the title has not changed since the first issue, Crossref, OpenAlex and the library catalogue recording identical text and J Clin Res Pediatr Endocrinol as the citation abbreviation, and the journal is a separate publication from the longer established Journal of Pediatric Endocrinology and Metabolism.刊名用词自第一期起未曾改动，Crossref，OpenAlex 与图书馆目录记录的题名完全一致，引用简称作 J Clin Res Pediatr Endocrinol，它与创刊更早的 Journal of Pediatric Endocrinology and Metabolism 是两种不同刊物。

Editors

• Abdullah Bereket of Marmara University Faculty of Medicine holds the editor-in-chief post, having founded the paediatric endocrinology division at that institution in 1999 and led its subspecialty programme since, with published interests in precocious puberty, obesity, vitamin D and insulin-like growth factors.现任主编是 Marmara University Faculty of Medicine 的 Abdullah Bereket，他于 1999 年创建该校儿科内分泌分部并主持亚专科项目至今，所列研究兴趣为性早熟，肥胖，维生素 D 与胰岛素样生长因子。
• His training began at Ankara University Medical School in 1986 and led through paediatric residency to subspecialty study in New York between 1991 and 1996, he chaired the Turkish society as president from 2003 to 2005, and the European Society for Paediatric Endocrinology gave him its Outstanding Clinician Award in 2022.其受训自安卡拉大学医学院 1986 年开始，经儿科住院培训后于 1991 至 1996 年在纽约完成亚专科训练，2003 至 2005 年出任土耳其学会主席，欧洲儿科内分泌学会于 2022 年授予其 Outstanding Clinician Award。
• The honorary editor is Feyza Darendeliler of Istanbul University, president of the society since 2014, who served on the council of the European society, edited its newsletter and took the same clinical award in 2017.荣誉主编为 Istanbul University 的 Feyza Darendeliler，自 2014 年起担任学会主席，曾任欧洲学会理事会成员与该会通讯编辑，并于 2017 年获得同一临床奖项。
• Nine associate editors handle submitted manuscripts, five of them at Turkish medical schools, Marmara, Ege, Dokuz Eylül, Hacettepe and Acıbadem, with responsibility divided by clinical subject.副主编共 9 人分管来稿，其中 5 人任职于土耳其医学院校，即 Marmara，Ege，Dokuz Eylül，Hacettepe 与 Acıbadem，分工按临床主题划定。
• Two associate editors sit outside Türkiye, Aneta Gawlik-Starzyk of the Medical University of Silesia in Katowice, who chairs the Turner syndrome working group of the European society, and Jan Idkowiak of the University of Birmingham, who works on androgen excess and disorders of sex development.2 位副主编任职土耳其以外，一是卡托维兹西里西亚医科大学（Medical University of Silesia）的 Aneta Gawlik-Starzyk，主持欧洲学会的 Turner 综合征工作组，二是伯明翰大学（University of Birmingham）的 Jan Idkowiak，主攻雄激素过多与性发育异常。
• Subject coverage among the remaining associate editors runs from type 1 diabetes technology and monogenic diabetes to lipodystrophy, pediatric genetics, metabolic bone disease and GNAS related disorders, and from neonatal screening programmes to thyroid and growth disorders.其余副主编的分工从 1 型糖尿病技术与单基因糖尿病延伸到脂肪萎缩，儿科遗传学，代谢性骨病与 GNAS 相关疾病，也覆盖新生儿筛查项目以及甲状腺与生长障碍。
• Three specialist posts stand beside the board, a social media editor, Saygın Abalı at Acıbadem Mehmet Ali Aydınlar University, an English language editor and assistant to the editor-in-chief, Jeremy Jones in Kocaeli, and a statistical consultant, Güven Özkaya of Bursa Uludağ University.编队另设 3 个专门职位，社交媒体编辑由 Acıbadem Mehmet Ali Aydınlar University 的 Saygın Abalı 担任，英语文字编辑兼主编助理是 Kocaeli 的 Jeremy Jones，统计顾问来自 Bursa Uludağ University 的 Güven Özkaya。
• The ordinary editorial board carries two dozen members drawn from Turkish children's hospitals and from institutions in the United States, the United Kingdom, Poland, Italy, Brazil, Egypt, Bulgaria, the Czech Republic and Oman.常规编委约 24 人，来自土耳其的儿童医院以及美国，英国，波兰，意大利，巴西，埃及，保加利亚，捷克与阿曼的机构。
• Overseas members include Ali Kemal Topaloğlu of the University of Mississippi Medical Center, Murat Bastepe of Massachusetts General Hospital, Khalid Hussain of Great Ormond Street Hospital, Claudia Piano of the University Hospital of Verona and Zdeněk Šumník of Charles University in Prague.海外编委包括 University of Mississippi Medical Center 的 Ali Kemal Topaloğlu，Massachusetts General Hospital 的 Murat Bastepe，Great Ormond Street Hospital 的 Khalid Hussain，Verona 大学医院的 Cludia Piano 与布拉格查理大学（Charles University）的 Zdeněk Šumník。
• Manuscripts enter through the publisher's online system rather than an editor's mailbox, the editorial office answers queries at a journal address, and a revised paper returned more than two months after decision is processed as a new submission.稿件一律经出版方的在线系统提交而不走编辑私人邮箱，编辑部设有公开问讯地址，超过 2 个月修回的稿件按新投稿处理。
• Each paper is assigned to an associate editor by topic, that editor appoints at least two external reviewers under a double blind procedure, similarity software is run before review, and the editor-in-chief takes the final decision even when the reports disagree.每篇来稿按主题交由一位副主编处理，该副主编至少邀请两位外部评审，评审采双盲制且作者与评审互不知晓身份，送审前先以相似度软件查重，最终决定由主编作出，意见分歧时仍由编辑评估两份报告的科学依据。
• Reported speed is posted on the journal pages, roughly 26 days from submission to first decision and about 52 days to acceptance, with the DOAJ record noting around 20 weeks to publication and view counts above 300 thousand for 2025.时效数据公开列于期刊页面，自投稿至初审判定约 26 天，至最终录用约 52 天，开放获取期刊目录记录的出版周期约 20 周，2025 年阅读量逾 30 万次。
• Instructions require reporting checklists, CONSORT for randomised trials and MOOSE or QUOROM for syntheses of observational work, MeSH keywords from the National Library of Medicine and adherence to ICMJE recommendations, with separate policy pages for appeals, misconduct allegations, conflicts of interest, data availability and the use of artificial intelligence.作者指南要求随稿附报告规范清单，随机试验用 CONSORT，观察性证据综合用 MOOSE 或 QUOROM，关键词须取自美国国家医学图书馆的 MeSH 词表，并遵循国际医学期刊编辑委员会建议，另设申诉，不当行为指控，利益冲突，数据可得性与人工智能使用各专页。
• Accepted papers receive a DOI at once and appear in an ahead of print section before being placed in an issue, while correspondence continues after publication, recent letters having disputed infant head circumference reference values and an internal inconsistency between a reported 50th percentile and its LMS median录用文章即刻取得 DOI 并进入提前在线栏目，随后才排入卷期，出版后的通信仍在继续，近期来信质疑过婴儿头围参考数值，也指出刊文中第 50 百分位数与 LMS 中位数不符。^[2]