IET Systems Biology

IET Systems Biology is the systems biology title of the Institution of Engineering and Technology, launched in 2007 and published by Wiley since 2021 as a fully open access journal, with a 2025 Journal Impact Factor of 1.9.《IET 系统生物学》是英国工程技术学会（Institution of Engineering and Technology）旗下的系统生物学刊物，2007 年创刊，2021 年起交 Wiley 出版并转为完全开放获取，2025 年期刊影响因子为 1.9。

Its ground lies between cell biology and control engineering. A paper here usually turns a living cell or a tissue into a dynamical system that can be measured, modelled and, in the end, steered.刊物的立足点介于细胞生物学与控制工程之间。这里的论文通常把一个活细胞或一块组织转成可以测量，可以建模，并最终可以调控的动力系统。

Scope

• The aims statement is short and procedural. Work has to use systems- and signal-oriented approaches on intra-cellular and inter-cellular dynamics, and a genomic study is accepted only where its results can support modelling and simulation of cell behaviour.宗旨页写得简短而具体，稿件须用系统与信号导向的方法处理细胞内与细胞间动力学，纯基因组研究只有在结果能支撑细胞行为的建模与仿真时才被接受。
• Genomics, transcriptomics, proteomics and metabolomics supply the data end of the remit, alongside the older vocabulary of cells, tissue and the physiome.基因组学，转录组学，蛋白质组学与代谢组学构成范围的数据一侧，细胞与组织以及生理组这类较早的说法也仍在列。
• Molecular and cellular interaction is a standing topic, and so is the function of a gene, a cell or a protein read as part of a larger circuit rather than on its own.分子与细胞的相互作用是常设题目，基因与细胞以及蛋白质的功能同样在此，只是要求把它们放进更大的回路里考察。
• Networks and pathways take the largest share of the pages, from the reconstruction of a signalling cascade to the comparison of one pathway across species.网络与通路占去最多版面，从信号级联的重建，到同一条通路在不同物种间的比较，都有先例。
• Metabolism and cell signalling are treated as control problems as much as biochemical ones, with fluxes and concentrations followed over time.代谢与细胞信号既被当作生化问题，也被当作控制问题，通量与浓度按时间序列追踪。
• Dynamics, regulation and control sit at the centre of the remit, and papers on feedback, oscillation, bistability and the design of interventions belong here.动力学与调节以及控制处在范围的中心，反馈，振荡，双稳态与干预设计一类稿件都归此处。
• Systems, signals and information give the journal its engineering vocabulary, borrowed from communication theory and applied to noisy channels inside the cell.系统，信号与信息为刊物提供工程学的词汇，这些词取自通信理论，被用到胞内那些带噪声的通道上。
• Experimental data analysis has its own place, on condition that the statistics serve a dynamical reading of the data rather than a description alone.实验数据分析自有其位，条件是统计要为数据的动力学解读服务，只作描述不算。
• Mathematical modelling, simulation and theoretical analysis form the methodological core, and a model that is never compared with measurement is unlikely to survive review.数学建模，仿真与理论分析构成方法核心，从不与实测对照的模型很难通过评审。
• Prediction and control of biological systems are named in the scope, which puts the title nearer to control engineering than most journals in systems biology.生物系统的预测与控制写在宗旨里，这一点使本刊比多数系统生物学刊物更靠近控制工程。
• Methods, databases, tools and algorithms for modelling are welcome, and reconstruction software and standards for exchanging models fall under the same heading.建模所需的方法，数据库，工具与算法都在欢迎之列，重建软件与模型交换标准也算在这一条里。
• Modelling, analysis and control of biological networks close the list, a heading broad enough to cover gene regulatory circuits, metabolic maps and cell signalling graphs.生物网络的建模，分析与控制收束这份清单，这一条宽到可以装下基因调控回路，代谢图谱与细胞信号图。
• Synthetic biology and bioengineering built on systems biology appear at the end of the scope, and reviews of that borderland are accepted as well.建在系统生物学之上的合成生物学与生物工程列在宗旨末尾，这类交叉地带的综述同样接受。

History

• Volume 1, number 1 appeared in January 2007, and the opening editorial of that issue is signed R. Iyengar.第 1 卷第 1 期在 2007 年 1 月面世，开篇社论由（R. Iyengar）署名。^[1]
• The publisher was the Institution of Engineering and Technology, the British body formed in 2006 from the merger of the Institution of Electrical Engineers and the Institution of Incorporated Engineers, and the imprint read Stevenage.出版方是英国工程技术学会，这家机构由电气工程师学会（Institution of Electrical Engineers）与联合工程师学会（Institution of Incorporated Engineers）于 2006 年合并而成，当时的出版地写作斯蒂夫尼奇（Stevenage）。
• Six issues a year were the rule from the start, and Crossref holds that grid without a break from 2007 to 2024. The dated issue records, from volume 7 onward, put them in February, April, June, August, October and December.创刊起就是一年六期，Crossref 的期号记录从 2007 年排到 2024 年没有断过，凡带日期的期号（第 7 卷起）都落在 2 月，4 月，6 月，8 月，10 月与 12 月。
• Volume numbers run one to a year, so volume 1 is 2007, volume 18 is 2024, volume 19 is 2025 and volume 20 is 2026.卷号与年份一一对应，第 1 卷是 2007 年，第 18 卷是 2024 年，第 19 卷是 2025 年，第 20 卷是 2026 年。
• One year broke that pattern in a small way. In 2022 the third and fourth issues of volume 16 were combined into a single number, so five printed issues covered six slots.有一年小小地破了例，2022 年第 16 卷把第 3 期与第 4 期并作一期，六个期号只出了五册。
• In 2021 the title changed hands. The National Library of Medicine now records the imprint as Oxford, Wiley, 2021 onwards, where it had read Stevenage, Institution of Engineering and Technology.2021 年出版权换了手，美国国家医学图书馆（National Library of Medicine）的出版项由斯蒂夫尼奇的工程技术学会改为牛津的 Wiley，起始年为 2021。
• That same year the whole IET list left the subscription model. The society and Wiley moved every IET journal, hybrid ones included, to an author-pays open access footing from the 2021 volume onward.同一年，IET 整套刊物退出订阅模式，学会与 Wiley 把旗下所有期刊连同混合型刊一并改为作者付费的开放获取，自 2021 年卷起对新投稿生效。
• The Directory of Open Access Journals dates the open access status to 2021, and Clarivate counts every 2025 paper as gold open access.开放获取期刊目录（Directory of Open Access Journals）把开放获取的起始年记为 2021，Clarivate 则把 2025 年的论文全部计为金色开放获取。
• Authors choose a Creative Commons licence at acceptance. CC BY is the default, and CC BY-ND, CC BY-NC and CC BY-NC-ND are the alternatives on offer.作者在录用时选择知识共享许可，默认是 CC BY，另有 CC BY-ND 与 CC BY-NC 以及 CC BY-NC-ND 三种可选。
• The article processing charge recorded by the same directory is 2400 US dollars, and no further fee, page charge or colour charge is listed.同一目录记录的论文处理费为 2400 美元，此外没有别的收费，版面费与彩图费都不在列。
• Issue numbering stopped being subdivided at the start of 2025. Volume 19 carries a single issue dated January, and the 52 papers of that year were all gathered into it.期号在 2025 年初不再细分，第 19 卷只有一期，标 1 月，当年 52 篇论文全部收进这一期。
• Volume 20 follows the same plan. Its one issue is dated January 2026 and already holds 35 papers, with the volume still open.第 20 卷沿用同一办法，唯一一期标 2026 年 1 月，已经收了 35 篇，卷内仍在增补。
• Indexing came early. MEDLINE and PubMed list the title from volume 1, number 1 of January 2007, PubMed Central holds the full text, and CLOCKSS and Portico keep the archive.收录来得早，MEDLINE 与 PubMed 自 2007 年 1 月的第 1 卷第 1 期起收录，PubMed Central 存有全文，CLOCKSS 与 Portico 负责长期存档。
• The impact factor has moved little in five years, standing at 1.615 in 2021, 1.468 in 2022 and 1.9 in each of 2023, 2024 and 2025, against a five-year figure of 2.0.影响因子五年间变动不大，2021 年为 1.615，2022 年为 1.468，2023 年至 2025 年连续三年为 1.9，五年影响因子是 2.0。
• Citation totals are modest. The 2025 count is 570, the cited half-life is 6.3 years, the Journal Citation Indicator is 0.41, and the title sits at the 33.6th percentile.被引总量不大，2025 年为 570 次，被引半衰期 6.3 年，期刊引证指数 0.41，百分位为 33.6。
• Output has swung with the years. Crossref counts 38 papers for 2007, 37 for 2015, a low of 15 for 2022, and 52 for 2025.发文量逐年摆动，Crossref 记 2007 年 38 篇，2015 年 37 篇，2022 年降到 15 篇的低点，2025 年回到 52 篇。
• The identifier scheme changed twice. Early papers use the colon form 10.1049/iet-syb:2008xxxx, later ones the dotted form 10.1049/iet-syb.2015.0037, and the current series runs under 10.1049/syb2.标识符改过两次，早期论文用冒号式的编号「10.1049/iet-syb:2008xxxx」，其后改用点式「10.1049/iet-syb.2015.0037」，现行序列则以「10.1049/syb2」开头。

Editors

• Kwang-Hyun Cho, of the Department of Bio and Brain Engineering at KAIST, was announced by his own university as the incoming editor-in-chief, with the editorial process passing to him by 2012.韩国科学技术院（KAIST）生物与脑工程系的（Kwang-Hyun Cho）由校方公告宣布出任主编，评审流程在 2012 年前交到他手上。
• His own field is systems science applied to biomedicine, with molecular systems biology as the main line and bio-inspired engineering derived from it as a second.他的本行是把系统科学用到生物医学，分子系统生物学是主线，由此衍生的仿生工程是另一条。
• A December 2014 editorial in the journal carries his name, which puts the middle of his tenure on the record.2014 年 12 月的社论以他的名字署名，任期的中段因此有据可查。^[2]
• The IET still named him editor-in-chief in December 2020, when it announced the move to author-pays publishing for the following volume.2020 年 12 月 IET 宣布次年改行作者付费出版时，仍把他列为主编。
• Guest editors carry the themed issues. Luonan Chen signed the guest editorial of October 2013, which opened a collection on network biology.专辑由客座编辑主持，2013 年 10 月的客座社论由（Luonan Chen）署名，为一批网络生物学稿件开篇。^[3]
• Xing-Ming Zhao took a two-part collection in 2014, one part on network biology in translational bioinformatics and a second on network construction and mining.2014 年，（Xing-Ming Zhao）主持了一个分两期刊出的专辑，上半部讲转化生物信息学中的网络生物学，下半部讲网络构建与挖掘。
• Diego di Bernardo signed the guest editorial of October 2016, part of a run of guest-edited collections that began in 2013.2016 年 10 月的客座社论由（Diego di Bernardo）署名，客座编辑组稿的做法从 2013 年延续下来。
• Luonan Chen, who holds posts at the Chinese Academy of Sciences and at Shanghai Jiao Tong University, is listed on the editorial board from 2010 in his own institutional profile.（Luonan Chen）在中国科学院与上海交通大学任职，其所在机构的履历页记他自 2010 年起担任本刊编委。
• Review is single anonymous. Referees are not named to authors, and the author guidelines describe the process in those terms.评审采单盲制，审稿人不向作者披露，作者指南对流程的说明就是这个口径。
• Submissions go through ScholarOne, the manuscript system that the IET moved its whole journal list onto alongside the transfer to Wiley.稿件经 ScholarOne 提交，IET 在与 Wiley 交接的同时把整套刊物迁到了这个稿件系统。