Human Molecular Genetics

Human Molecular Genetics is a biweekly peer-reviewed journal published by Oxford University Press, covering molecular genetics and human disease. Founded in 1992, it is a leading journal publishing original research in all areas of human molecular genetics, with a 2025 impact factor of 3.1, indexed in SCIE.《人类分子遗传学》（Human Molecular Genetics, 简称 Hum. Mol. Genet.）是由牛津大学出版社出版的双周刊同行评审期刊，涵盖分子遗传学与人类疾病。该刊创刊于 1992 年，是发表人类分子遗传学各领域原创研究的顶级期刊，2025 年影响因子为 3.1，被 SCIE 收录。

Scope

The journal's stated aim is to publish original research papers on all topics relevant to human molecular genetics, with its official scope covering:刊物官方宗旨为发表与人类分子遗传学相关所有主题的原创研究论文，官方声明的征稿范围包括：

• Human genetics and disease: original research on the genetic basis of human diseases, including monogenic disorders, complex diseases, and cancer genetics.人类遗传学与疾病： 关于人类疾病遗传基础的原创研究，包括单基因疾病、复杂疾病与癌症遗传学。
• Functional genomics: studies on the functional characterization of genes and genetic variants, including gene expression regulation, epigenomics, and the molecular mechanisms of genetic disease.功能基因组学： 关于基因与遗传变异功能表征的研究，包括基因表达调控、表观基因组学与遗传病分子机制。
• Population and evolutionary genetics: research on human genetic variation, population genetics, evolutionary genetics, and the genetic architecture of human traits.群体与进化遗传学： 关于人类遗传变异、群体遗传学、进化遗传学以及人类性状遗传结构的研究。
• Molecular and cellular mechanisms: studies on the molecular and cellular mechanisms underlying genetic disorders, including animal models, in vitro systems, and therapeutic approaches.分子与细胞机制： 关于遗传疾病分子与细胞机制的研究，包括动物模型、体外系统与治疗方法。
• Article types: the journal publishes original research articles, review articles, brief communications, and methodology papers in human molecular genetics.栏目设置： 该刊发表人类分子遗传学领域的原创研究论文、综述、短讯与方法学论文。

History

• Founding: the journal was established in 1992 to provide a dedicated publication venue for the rapidly growing field of human molecular genetics.创刊： 该刊于 1992 年创刊，为快速发展的人类分子遗传学领域提供专属发表平台。
• Oxford University Press: Human Molecular Genetics is published by Oxford University Press, ensuring high editorial standards and broad international distribution.牛津大学出版社： 《人类分子遗传学》由牛津大学出版社出版，确保高编辑标准与广泛的国际传播。
• Leading genetics journal: throughout its history, the journal has become a leading journal in human molecular genetics, publishing foundational research on the genetic basis of human disease.顶级遗传学期刊： 在其发展历程中，该刊已成为人类分子遗传学领域的顶级期刊，发表关于人类疾病遗传基础的基础性研究。
• Publication frequency: the journal publishes biweekly, ensuring rapid dissemination of important advances in human molecular genetics.出版频率： 该刊每两周出版一期，确保人类分子遗传学重要进展的快速传播。

Editors

The journal is led by an editor-in-chief supported by topic editors and an editorial board:该刊由主编领导，专题编辑与编委会协助工作：

• Editor-in-chief: Mark Seielstad, Professor at the University of California, San Francisco, United States, serves as the editor-in-chief.主编： 美国加州大学旧金山分校教授马克·塞尔斯塔德（Mark Seielstad）担任主编。
• Topic editors: the editor-in-chief is supported by topic editors with expertise across major areas of human molecular genetics.专题编辑： 主编由具有人类分子遗传学主要领域专长的专题编辑协助。
• Editorial board: the journal has a distinguished international editorial board comprising geneticists and molecular biologists from leading institutions worldwide.编委会： 该刊拥有杰出的国际编委会，成员为来自全球顶尖机构的遗传学家与分子生物学家。
• Open access option: authors can choose to publish open access in this journal, making their articles freely available to readers upon publication in exchange for an article processing charge.开放获取选项： 作者可选择在该刊发表开放获取文章，使论文发表后即向读者免费开放，并支付文章处理费。