Genome Research
Genome Research (commonly abbreviated as ''Genome Res.') is a peer-reviewed academic journal published by Cold Spring Harbor Laboratory Press, issued monthly. It is a principal venue in genomics with a long-standing emphasis on genome-scale analyses, chromatin structure and function, epigenomics, systems genetics and proteomics《基因组研究》（Genome Research'，常用缩写为 Genome Res.'''''）是冷泉港实验室出版社（Cold Spring Harbor Laboratory Press）出版的同行评审学术期刊，月刊发行。该刊是基因组学领域的主要发表渠道，重点关注基因组尺度的分析、染色质结构与功能、表观基因组、系统遗传学与蛋白质组学，创刊时曾用另一个刊名。 the title was known under a different name at its founding.
Scope
Since 2011 the journal has been continuously published without traditional volumes or issues, and it describes itself as an international peer-reviewed journal publishing studies on the structure, function, biology and evolution of genomes of all organisms. The formulation indicates that the genome itself is the object of study rather than any single group of organisms. Its principal subject areas include:本刊自二〇一一年起连续出版，不设传统卷期与出版周期，官方定位为发表所有生物的基因组之结构、功能、生物学与演化研究的国际同行评审期刊。这一表述说明它不以任何单一生物门类为限，而把基因组本身作为研究对象。收文覆盖的主要方向包括：[1]
- Genome-scale analysis: whole-genome sequencing and resequencing, genome assembly and alignment, variant detection and annotation.基因组尺度分析： 全基因组测序与重测序、基因组组装与比对、变异检测与注释。
- Chromatin and the epigenome: chromatin structure and the three-dimensional genome, the distribution and function of epigenetic marks, and regulatory elements.染色质与表观基因组： 染色质结构与三维基因组、表观遗传标记的分布与功能、基因调控元件。
- Gene expression and regulation: transcriptomic analysis, splicing and post-transcriptional regulation, and gene interaction networks.基因表达与调控： 转录组分析、剪接与转录后调控、基因互作网络。
- Systems genetics: quantitative trait locus mapping, population genetics, and genotype–phenotype association.系统遗传学： 数量性状位点定位、群体遗传学、基因型与表型关联。
- Comparative genomics and evolution: genome comparison across species, gene family evolution, and genomic rearrangement and speciation.比较基因组学与演化： 物种间基因组比较、基因家族演化、基因组重排与物种形成。
- Proteomics and multi-omics integration: proteomes and interactomes, integration of cross-omics data, and multi-omics methods and tools.蛋白质组与多组学整合： 蛋白质组与相互作用组、跨组学数据整合、多组学方法与工具。
The journal is hybrid with delayed open access: articles become free online six months after publication, while authors choosing immediate open access pay an article processing charge plus a separate publication service charge. The publisher reports only an average review cycle of thirty days, and publishes neither impact factor, CiteScore nor acceptance rate.本刊属混合出版并附延迟开放：论文发表六个月后免费在线，选用立即开放获取须支付文章处理费及另收的出版服务费。出版社只公布平均审稿周期三十天，不公布影响因子、引用分数与录用比例。[2]
History
- Founding context (1991): the journal was founded in August 1991 under the title PCR Methods and Applications and was published by Cold Spring Harbor Laboratory Press from the outset, the publisher never having changed. The driving figure behind its creation was James D. Watson, who established the journal in negotiation with the press to track the rapidly evolving technology of the polymerase chain reaction.创刊背景（1991年）： 本刊于 1991 年 8 月创刊，创刊时的刊名为《聚合酶链式反应方法与应用》，由冷泉港实验室出版社直接出版——出版方自创刊起未曾变更。推动创办这一刊物的是詹姆斯·沃森，他与出版社协商后设立此刊，以配合当时正迅速演进的聚合酶链式反应技术。[3]
- Editors and format at founding: an advertisement printed in the journal at that time names Judy Cuddihy as founding editor, with David Bentley, Richard Gibbs, Eric Green and Richard Myers as deputy editors. The journal appeared four times a year at first, shifted to bimonthly in October 1993, and ran through volume 4, number 6 in June 1995.创刊期的编辑与形态： 创刊期印于刊内的广告页署名创刊主编朱迪·卡迪希，副编辑为戴维·本特利、理查德·吉布斯、埃里克·格林与理查德·迈尔斯。创刊时为每年四册，至一九九三年十月改为双月刊，一九九五年六月出至第 4 卷第 6 日止。[4]
- Renaming and a widened remit (1995): from August 1995 the journal appeared under its present title, Genome Research, continuing the earlier title with unbroken volume numbering, the first issue of the new title being volume 5, number 1. The change was not merely a new name: the remit widened from a particular technical method to genomics as a whole, which is what the press announced that year. The National Library of Medicine likewise records the journal as continuing the earlier title.更名与定位扩展（1995年）： 1995 年 8 月起以现名《基因组研究》出版，接续原刊且卷号连续，新刊第一期为第 5 卷第 1 期。这次更名不只是换名，而是把刊物的范围由特定技术方法扩展到整个基因组学，出版社当年的新刊公告即以此为宣示内容。美国国立医学图书馆的编目亦明确记载本刊续承原刊。[5]
- Catalogue lineage: the National Library of Medicine record begins at volume 5, number 1 of August 1995 and notes continuation of PCR Methods and Applications, whose own ISSN is 1054-9803 and which ran until 1995.编目沿革： 美国国立医学图书馆编目起始于一九九五年八月第 5 卷第 1 期，并注明续承《聚合酶链式反应方法与应用》，该前身刊的国际标准刊号为 1054-9803，止于一九九五年。[6]
Editors
The journal has no editor-in-chief. It is run by an executive editor with seven subject editors covering separate areas, assisted by a deputy editor and a senior assistant editor. That subject-wise structure suits a title of wide disciplinary span and fast-moving methods, with manuscripts routed to a specialist in the relevant field and the editorial office's role weighted towards organization and momentum. The publisher publishes neither an acceptance rate nor a time to first decision for the title.本刊不设主编一职，而实行执行编辑统领、七位学科编辑分领域把关的架构，另配副编辑与高级助理编辑各一位。这一分领域结构与本刊学科跨度大、方法更新快的特点相配：不同门类的稿件交由相应领域的学者判断，编辑部的角色更偏向组织与推进。出版社不公布本刊的录用比例与首决时长。[7]
- Hillary E. Sussman (executive editor): executive editor at Cold Spring Harbor Laboratory Press, with overall responsibility for the journal's editorial flow and publishing execution.希拉里·萨斯曼（执行编辑）： 冷泉港实验室出版社在职执行编辑，统筹本刊的编辑流程与出版执行。[8]
- The subject editors: seven subject editors drawn from different institutions and areas, among them Aravinda Chakravarti, Evan E. Eichler, Anne C. Ferguson-Smith, Richard A. Gibbs, Jian Ma, Kateryna D. Makova and Richard M. Myers, together forming the body that actually judges submissions.学科编辑阵容： 七位学科编辑分别来自不同机构与领域，包括阿拉瓦马·哈克拉瓦蒂、埃文·艾希勒、安妮·弗格森-史密斯、理查德·吉布斯、简·马、卡特琳娜·马科娃与理查德·迈尔斯，他们构成实际的选稿判断力量。[8]
- Founding editor: Judy Cuddihy was the editor at founding, a professional editor of the press创刊主编： 朱迪·卡迪希是创刊期的主编，属出版方专职编辑；一九九五年出版社宣布新刊时，仍以其名作为稿件接收地址的负责人。 when the press announced the new title in 1995 she was still named as the person to whom manuscripts should be addressed.[5]
- Standing in the field: one of the principal venues for methodological and database papers in genomics, and its papers routinely become the baseline literature for later tools and data-analysis methods, a role it played especially through the structural genomics phase of the cryo-electron microscopy era.学科地位： 本刊是基因组学方法学与数据库类论文的主要发表渠道之一，其论文常成为后续工具开发与数据分析方法的基准文献，在冷冻电镜时代的结构基因组学阶段尤其承担方法基准的角色。[1]