Genetics Research

Genetics Research is a fully open access journal of human and animal genetics, issued by John Wiley & Sons, which came to the title through Hindawi after the 2020 volume. Volume 1 appeared in 1960 as Genetical Research, and the 2025 Journal Impact Factor stands at 1.9, 140th of 192 titles in genetics and heredity.《遗传学研究》（Genetics Research）是一本全面开放获取的人类与动物遗传学刊物，现由 John Wiley & Sons 出版，此前经 Hindawi 接手 2020 年卷之后的出版。第 1 卷于 1960 年以 Genetical Research 之名问世，2025 年影响因子为 1.9，在遗传学与遗传类目 192 种刊物中列第 140 位。

Continuous volume numbering ties the present title to the Cambridge run, and the 2025 record counts 1982 citations, 24 citable items in the year and a cited half-life of 23.4 years, the last figure propped up by six decades of backfile.连续的卷号把现名同剑桥时期的旧刊连成一套。2025 年统计全刊累计被引 1982 次，当年可引用论文 24 篇，引用半衰期 23.4 年，末一项靠六十年的过刊撑着。

Scope

• The journal describes itself as a key forum for original research on all aspects of human and animal genetics, reporting findings on genomes, genes, mutations and molecular interactions and extending to developmental, evolutionary and population genetics as well as ethical, legal and social questions.刊物自述为人类与动物遗传学各方面原创研究的重要论坛，刊载基因组、基因、突变与分子相互作用的研究结果，并延伸到发育遗传学、进化遗传学与群体遗传学，兼及伦理、法律和社会层面的讨论。
• Medical genetics supplies much of the current flow. Papers map single-gene disorders, weigh variants of uncertain significance and report families or small cohorts in which a candidate change segregates with disease.医学遗传学构成当下来稿的一大部分。论文梳理单基因病的致病机制，评估意义未明的变异，也报告候选变异与疾病共分离的家系或小队列。
• Karyotype work keeps a place too, with survey papers tabulating incidental chromosomal abnormalities found in routine peripheral blood analysis and asking what such findings mean for counselling.核型分析仍占一席之地，综述性论文把常规外周血检查中偶见的染色体异常列出成表，并追问这类发现对遗传咨询的意义。
• Sequencing technology is the stated focus. Next-generation approaches combined with bioinformatic analysis are named in the aims as the route to a more detailed view of how genes act in tissues and how they act together in development and in disease.测序技术是刊物明言的着力点。宗旨把新一代测序与生物信息学分析的结合写成路径，用来更细致地看清基因在组织中如何起作用，以及在发育和疾病中如何共同起作用。
• Computational studies and novel methods are listed as article types in their own right, so a pipeline paper or a reanalysis of public data can be judged on the strength of its design rather than on bench novelty.计算研究与新方法被单列为一种稿件，流程性论文或对公共数据的再分析，可以按设计本身的可靠性来衡量，不必依赖实验台上的新意。
• Complex trait genetics runs through recent volumes, with genome-wide association, polygenic scoring and heritability partitioning applied to traits that range from stature to osteoarthritis.复杂性状遗传学贯穿近年的各卷，全基因组关联、多基因评分与遗传力拆分被用于身高到骨关节炎一类的性状。
• Mendelian randomization has become one of the most common designs in the journal, using genetic variants as instruments to test whether a circulating lipid, a protein or an inflammatory marker sits on the causal path to a disease.孟德尔随机化已成为刊物里最常见的设计之一，以遗传变异作工具变量，检验某种血脂、蛋白或炎症标志物是否位于疾病的因果链上。
• Population genetics and human evolution appear as demographic reconstruction, admixture history and scans for selection, often built on public reference panels and on ancient or present-day genomes.群体遗传学与人类演化以人口重建、混合历史与选择扫描的形式出现，常建立在公共参考面板以及古今基因组之上。
• Molecular and developmental genetics, including the evo-devo tradition, treats the regulatory logic of body plan and organ form, a strand the journal has carried since its Cambridge years.分子遗传学与发育遗传学，包括演化发育生物学一脉，处理体构与器官形态的调控逻辑，这条线从剑桥时期一直延续至今。
• Quantitative and statistical genetics remains in the remit as well, covering the design of selection experiments, the estimation of variance components and the mixed models that now carry most heritability work.数量遗传学与统计遗传学同样在范围内，涵盖选择实验的设计、方差组分的估计，以及如今承担多数遗传力工作的混合模型。
• Behavioural genetics and environmental genetics close the list of named topics, the first asking how much of a behavioural difference is heritable, the second how genotype and exposure combine.行为遗传学与环境遗传学收在明列主题的末尾，前者追问行为差异有多少可以遗传，后者追问基因型与环境暴露如何叠加。
• Cancer genetics has grown into a visible share of the pages, with somatic mutation profiles, germline predisposition panels and tumour transcriptomes analysed for prognosis or for immune infiltration.肿瘤遗传学在版面上占的份额渐多，体细胞突变谱、胚系易感基因组合与肿瘤转录组被用来分析预后，或用来刻画免疫浸润。
• Epigenetics and transcriptomics now arrive together, and single-cell datasets are used to ask which cell type in a tissue carries the signal that a whole-tissue average had flattened out.表观遗传学与转录组学如今常一并出现，单细胞数据被用来追问组织中哪一种细胞携带了被整体平均抹平的信号。
• Ethical, legal and social aspects are named in the aims rather than left implicit, which leaves room for papers on genetic testing, consent and the handling of incidental findings.伦理、法律与社会层面写进了宗旨，基因检测、知情同意与偶然发现的处理因此也留有版面。
• The article types are set out plainly, covering original work, review articles, short papers, computational studies, and novel methods and techniques for research on humans and on established model organisms.稿件类型列得直接，包括原创论文、综述、短篇论文、计算研究，以及针对人类与成熟模式生物的新方法与新技术。

History

• Volume 1, number 1 came out in February 1960 from Cambridge University Press, and three numbers made a volume in those years, dated February, July and November.第 1 卷第 1 期于 1960 年 2 月由 Cambridge University Press 印出，最初三期为一卷，分别标 2 月、7 月与 11 月。
• That first volume reads as a portrait of experimental genetics at the time, with selection for body size in mice, inbreeding depression in litter size and the T-locus, alongside ecological genetics of growth in Drosophila and heterokaryosis in Coprinus.这一卷像当年实验遗传学的写照，有小鼠体重的选择实验、产仔数的近交衰退与 T 位点，也有果蝇生长的生态遗传学与鬼伞属的异核现象。
• Mutagenesis filled a good share of the early pages, from alkylating agents and triethylenemelamine to X-ray sensitivity of foetal gonads, in keeping with a period whose questions were put at the level of the germ cell.诱变研究占了早期版面的不小部分，从烷化剂与三亚乙基密胺到胎鼠性腺对 X 射线的敏感性，那个时期的问题都落在生殖细胞这一层。
• One volume a year served 1960 to 1965. From 1966 the pace doubled, volumes 7 and 8 both dated 1966, and two volumes a year carried the journal through 2007, when volume 89 closed.1960 年至 1965 年每年出一卷。此后节奏加倍，1966 年出现第 7 卷与第 8 卷两卷，每年两卷的格局一直延续到 2007 年第 89 卷收尾。
• The title changed inside that volume. Its December 2007 number already carried Genetics Research on the cover, and volume 90, number 1 of February 2008 opened under the new name with the numbering unbroken.改名发生在这一卷之内。2007 年 12 月的一期封面上已印 Genetics Research，2008 年 2 月的第 90 卷第 1 期以新名开卷，卷号没有中断。
• Neither ISSN changed with the title, so 0016-6723 for print and 1469-5073 for the electronic edition run across the divide, and a reader following a citation from 1975 to 2025 stays inside one identifier pair.两个刊号都没有随刊名更换，纸本 0016-6723 与电子版 1469-5073 跨越了这次改名，从 1975 年追到 2025 年的读者始终落在同一对号码里。
• Between 2008 and 2020 the journal settled at one volume a year, volumes 90 to 102, all of them under the Cambridge imprint and all registered with the prefix 10.1017.2008 年至 2020 年回到每年一卷，第 90 卷到第 102 卷都留在剑桥的印记下，全部登记在 10.1017 前缀。
• Hindawi took over with the 2021 volume, and the arrangement changed with the owner. The volume number became the calendar year, articles received number-style identifiers in place of page ranges, and the prefix moved to 10.1155.2021 年卷起由 Hindawi 接手，编排随东家一并改动。卷号改用公历年，文章以编号代替页码区间，前缀移到 10.1155。
• Wiley absorbed Hindawi and the imprint passed to John Wiley & Sons in 2024, a change recorded in the National Library of Medicine imprint, while the 10.1155 prefix and the year-numbered volumes stayed, with the journal code genr joining the DOI path partway through the 2024 volume.Wiley 收购 Hindawi 之后，出版印记于 2024 年转到 John Wiley & Sons，美国国家医学图书馆的出版项记下了这一改动，而 10.1155 前缀与按年编号的卷次保持不变，刊物代码「genr」从 2024 年卷中段开始出现在 DOI 路径里。
• Sixty-one years produced 102 volumes at Cambridge, and that sequence has not been revived. A 2026 paper is cited as volume 2026, so anyone reading a reference list can see where the old numbering stops.剑桥时期六十一年共出 102 卷，那套序号此后再未接续。2026 年的论文标作第 2026 卷，翻阅参考文献表的人一眼就能看出旧编号停在哪里。
• Output has been uneven across the transition. Volume 102 (2020) lists seven items, the 2021 volume thirteen, and the 2025 count records 24 citable papers, with the 2026 volume already past thirty.交接前后的载文量并不齐整。第 102 卷（2020）只有七篇，2021 年卷十三篇，2025 年可引用论文 24 篇，2026 年卷已过三十篇。
• Impact factors for the last five years read 1.588 for 2021, 1.375 for 2022, 1.4 for 2023, 2.1 for 2024 and 1.9 for 2025, against a five-year figure of 2.2.近五年影响因子依次为 2021 年 1.588、2022 年 1.375、2023 年 1.4、2024 年 2.1 与 2025 年 1.9，2025 年的五年影响因子为 2.2。
• The 2025 placement is 140th of 192 in genetics and heredity, a Q3 position, with a Journal Citation Indicator of 0.5 and a percentile of 27.3.2025 年的位置是遗传学与遗传类目 192 种中的第 140 位，属 Q3，期刊引文指标 0.5，百分位 27.3。
• A cited half-life of 23.4 years is long for any biological title, and it reflects the Cambridge backfile, whose papers from the 1960s and 1970s still count among the citations a volume attracts.23.4 年的引用半衰期在任何生物学期刊里都算长，来源是剑桥时期的过刊，1960 年代与 1970 年代的论文至今仍计入各卷所获的引用。
• The subject matter moved with the field. Where volume 1 studied mice, Drosophila and fungi at the bench, the 2026 volume is dominated by human cohorts, public cancer datasets and variant annotation, a shift the editorial line has followed rather than resisted.题材随学科一同移动。第 1 卷在实验台上研究小鼠、果蝇与真菌，2026 年卷则由人类队列、公共肿瘤数据集与变异注释占据，编辑取向顺着这一移动走，未另设阻力。

Editors

• Editorial authority sits with an editor-in-chief and a board of handling editors, and each submission passes to one of them for the choice of referees and for the recommendation that goes forward.编辑权由主编与一组负责具体稿件的编辑共同掌握，每篇来稿分派给其中一位，由其约请评审并提出处理建议。
• Every article prints the name of the academic editor who handled it, so the working panel can be read off the papers themselves rather than from a single masthead page.每篇论文都在正文前部标出经办该稿的学术编辑，工作团队因此可以从论文里逐篇看出，不必依赖一页固定的编委名单。
• Refereeing is the gate that matters, since acceptance depends on reports written outside the editorial office, and the standing of the title in JCR and MEDLINE rests on that filter rather than on volume.真正的关口在外部评审，录用取决于编辑部之外的研究者所写的意见，刊物在 JCR 与 MEDLINE 里的位置靠这道筛子维持，与篇数无关。
• Much of what arrives now originates in clinical and bioinformatic groups, and a manuscript whose question falls outside human or animal genetics is returned before it reaches a referee.如今来稿多出自临床与生物信息团队，问题落在人类或动物遗传学之外的稿件，在送到评审手里之前就被退回。
• For a paper built on a variant or an association, the reports tend to fix on three points, namely whether the signal survives correction, whether the cohort is large enough to carry the claim, and whether the analysis can be rerun from what was deposited.建立在某个变异或关联之上的论文，评审通常盯住三点，信号能否通过校正，队列是否大到足以支撑结论，分析能否凭提交的材料重跑一遍。
• Article types are fixed and short, running from original research and reviews to short papers, computational studies and methods notes. A short paper carries a single finding that a full article would thin out.稿件类型固定而简短，从原创研究与综述到短篇论文、计算研究与方法札记。单一发现在长文里会被稀释，短篇正是为这类内容留的位置。
• Corrections appear as items of their own and are linked to the paper they repair, so the 2026 volume carries a correction to an osteoarthritis study beside the original.更正作为独立条目刊出，并与被更正的论文互相链接，2026 年卷里就有一条针对骨关节炎研究的更正，与原论文并列。
• Retractions follow the same pattern. A 2026 notice withdraws a microRNA paper on colon cancer proliferation, migration and invasion, and the notice remains a citable item rather than a silent deletion.撤稿走同样的路数。2026 年的一条撤稿声明撤回一篇关于结肠癌细胞增殖、迁移与侵袭的 microRNA 论文，声明本身作为可引用条目存在，不做无声删除。
• Publication is continuous. An accepted article receives its identifier and appears without waiting for an issue to be assembled, which is why the annual volume is a running record rather than a bundle dated at year end.出版是连续的。录用的文章拿到编号即可上线，不必等一期凑齐，年度卷因此是一份随时增补的记录，不是年底打包的一束。
• Almost every paper now carries a CC BY licence, a term that runs with the version of record and lets authors meet funder mandates without a separate agreement.如今几乎每篇论文都带 CC BY 许可，这一条款随正式版本生效，作者无须另签协议即可满足资助方的开放要求。
• Ethics handling follows the publisher's code, which rests on COPE guidance for authorship, competing interests and image integrity, and submissions are screened for text similarity before review.伦理事务依出版方的规范处理，作者身份、利益冲突与图像完整性都以 COPE 的准则为底，来稿在送审前先做文本相似度筛查。
• No subscription stands between a reader and the text and no page charge falls on authors. Production is met by an article processing charge, which is what keeps the whole archive open at the point of reading.读者与正文之间没有订阅门槛，作者也不承担版面费，生产费用由文章处理费支出，过刊因此在阅读端完全开放。