Current Drug Metabolism
Current Drug Metabolism (Curr. Drug Metab.) is a drug metabolism journal published by Bentham Science Publishers. Founded in 2000, it concentrates on metabolic pathways of drugs, pharmacokinetics and metabolism-related toxicity, appears monthly, and had a 2025 impact factor of 2.3.《当代药物代谢》(Current Drug Metabolism'''',缩写 Curr. Drug Metab.'')是本瑟姆科学出版社出版的药物代谢刊物,2000 年创刊。该刊以药物代谢途径、药代动力学与代谢相关毒性为主,现为月刊,二〇二五年影响因子为 2.3。
Scope
The journal's editorial stance is that a paper must concern what happens to a drug in the body: however novel the compound, it has to give empirical results on metabolic pathways, kinetic parameters or metabolism-related toxicity. Coverage runs across the whole chain of drug metabolism research and concentrates on:本刊的取稿立场是「围绕药物在体内的去向」:一篇论文不论化合物多么新颖,都要给出代谢途径、动力学参数或代谢相关毒性的实证结果。收文覆盖药物代谢研究的完整环节,重点包括:
- Drug metabolism: phase I and phase II metabolising enzymes, elucidation and comparison of metabolic pathways, identification and quantification of metabolites, and determination of enzyme kinetic parameters.药物代谢: 一相与二相代谢酶、代谢途径的阐明与比较、代谢物鉴定与定量、酶动力学参数测定。
- Pharmacokinetics: absorption, distribution, metabolism and excretion studies, physiologically based pharmacokinetic modelling, pharmacokinetic-pharmacodynamic relationships, and toxicokinetic assessment.药代动力学: 吸收分布代谢排泄研究、生理药代动力学模型、药动与药效的关联、毒代动力学评价。
- Drug interactions: enzyme inhibition and induction, transporter-mediated interactions, herb-drug interactions, and assessment of clinically significant interactions.药物相互作用: 酶抑制与诱导、转运体介导的相互作用、中草药与药物相互作用、临床意义上的相互作用评价。
- Drug transporters: uptake and efflux transporters, coordination of transport and metabolism, blood-brain barrier and placental transfer, and regulation and polymorphism of transporters.药物转运体: 摄取与外排转运体、转运与代谢的协同、血脑屏障与胎盘转运、转运体的调控与多态性。
- Species differences and extrapolation: metabolic differences between laboratory animals and humans, in vitro to in vivo extrapolation, choice of species and model validity, and methods of human prediction.种属差异与外推: 实验动物与人之间的代谢差异、体外到体内的外推、种属选择与模型合理性、人体预测方法。
- Bioactivation and toxicity: reactive metabolites and bioactivation, metabolite-mediated toxicity, mechanisms of liver injury, and target organ toxicity and dose-response.生物活化与毒性: 反应性代谢物与生物活化、代谢物介导的毒性、肝损伤机制、靶器官毒性与剂量反应。
The journal is hybrid, with open access articles appearing simultaneously on ScienceDirect. The publisher publishes neither review speed nor acceptance rate. The impact factor is in conflict within the publisher's own site: the announcements page gives 2.3, with 2.5 over five years, while another page shows 1.8本刊为混合出版,开放获取文章同步上线 ScienceDirect;出版方未公布审稿时效与录用比例;影响因子一项在官网内部存在冲突,期刊公告页列 2.3(五年 2.5),另一页显示 1.8,引用分数栏位列 4.4。 the CiteScore field gives 4.4.[1]
History
- Founding (2000): the journal was founded in 2000 under its present name, with no predecessor title and no renaming, so the founding year is also the year the present name took effect. The publisher's own journal history records neither a founder nor a founding rationale.创刊(2000年): 2000 年创刊,创刊即使用现名,无前身刊名亦无改名,创刊年即现名启用年;出版方公布的刊物沿革中未记载创刊人与创刊动因。[2]
- Volumes and scale: the journal appears monthly in print and online. Volume numbering has reached volume 27 in 2026, and the publisher lists past volumes and thematic issues on the journal page.卷期与体量: 本刊现为月刊,纸本与在线并行出版;卷号已排至第 27 卷(2026 年),出版方在期刊页列出历年的卷期与专刊主题。
- Metrics and indexing: the publisher's site gives an impact factor of 2.3 and a CiteScore of 4.4. The journal is indexed in Scopus, the Science Citation Index Expanded and MEDLINE.指标与收录: 官网列影响因子 2.3、引用分数 4.4;本刊被 Scopus、科学引文索引扩展版与 MEDLINE 收录。
Editors
The succession of editors is not synchronised across the publisher's own pages: the editorial board page and the journal page disagree on the present incumbent, so two accounts stand. Three editors can be traced since founding.本刊主编更替在官方页面上存在未同步的情况:编委会页与期刊页对现任主编的记载不一致,因此现任人选两说并存;可考的历任主编自创刊起有三任。[3]
- Present editor, two accounts: the editorial board page lists Yuwei Wang of the School of Pharmacy at Shaanxi University of Chinese Medicine, while the official 2025 directory still lists Ming Hu as editor-in-chief. Both records stand and the publisher has issued no correction.现任主编(两说并存): 编委会页列(Yuwei Wang)供职于陕西中医药大学药学院;2025 年官方期刊目录仍列(Ming Hu)为主编,两人记载并存,出版方未作出更正说明。
- Past editors: Ming Hu was the founding editor, serving from 2000 to about 2016历任主编: (Ming Hu)任首任主编,自 2000 年至约 2016 年;(Michael Sinz)约 2017 年至 2020 年在任;(Ming Hu)自 2021 年再度出任,与官方目录的记载一致。 Michael Sinz held the post from about 2017 to 2020 and Ming Hu returned to the editorship from 2021, consistent with the official directory.
- Role in the field: the journal is one of the few titles devoted solely to drug metabolism and has long been a concentrated channel for work on drug-metabolising enzymes, transporters and species extrapolation学科角色: 本刊是药物代谢领域少数以该主题单独设刊的刊物之一,长期作为药物代谢酶、转运体与种属外推研究的集中发表渠道,其综述常被药学与毒理学教材引用。 its reviews are frequently cited in pharmacy and toxicology teaching.