Chirality

Chirality is a monthly journal from Wiley, founded in New York in 1989 and now in its 38th volume, publishing research on the role of chirality in chemistry and biochemistry, with a 2025 Journal Impact Factor of 2.4 and a CiteScore of 5.9.《手性》是 Wiley 出版的月刊，1989 年在纽约创刊，2026 年出到第 38 卷，专门发表手性在化学与生物化学中所起作用的研究，2025 年期刊影响因子 2.4，CiteScore 5.9。

Scope

• The remit is the role of chirality in chemistry and biochemistry, judged through the biological, chemical, materials, pharmacological, spectroscopic and physical properties of chiral molecules.刊物的宗旨是手性在化学与生物化学中所起的作用，衡量角度取自手性分子的生物学性质与化学性质，材料与药理性质、光谱与物理性质同样计入。

• Papers come from physical, preparative synthetic and analytical chemistry, and from physics, pharmacology, clinical pharmacology, toxicology and the remaining biological aspects of chiral molecules.稿件来自物理化学、制备合成化学与分析化学，也来自物理学与药理学，临床药理学与毒理学一并受理，手性分子余下的生物学层面同样在内。

• Asymmetric synthesis heads the topic list, together with the development and characterization of chiral catalysts and the mechanistic questions attached to them.不对称合成排在选题清单首位，与之并列的是手性催化剂的研制与表征，以及附着其上的机理问题。

• Chiroptical spectroscopies make up the journal's signature block, ECD, VCD, OR, ROA and CPL among them, each taken at experimental, instrumental, theoretical and computational levels.手性光谱学构成刊物的招牌板块，ECD、VCD、OR、ROA 与 CPL 都在其列。实验与仪器是一侧，理论与计算是另一侧，两侧同样按研究受理。

• Instrument design and spectral calculation count as research in their own right, so a new detector or a new computational protocol is read on the same footing as a synthetic route.仪器设计与光谱计算本身就按研究对待，新探测器或新计算方案与一条合成路线同等看待。

• Separation gets both a preparative and an analytical side, through enantioselective chromatography and related techniques, liquid-liquid extraction and the crystallization of stereoisomers.分离在制备与分析两侧都设位置，对映选择性色谱与相关技术占一路，液液萃取与立体异构体结晶占另一路。

• Isolation and structural elucidation of natural products is a heading of its own, and the structural argument in such papers usually rests on the chiroptical methods above.天然产物的分离与结构解析单列一条，这类论文的结构论证多半要靠上面那几类手性光谱方法。

• Homochirality and spontaneous symmetry breaking in nature are treated as research subjects, not as background to laboratory practice.自然界的同手性与自发对称破缺按研究题目受理，不拿它给实验室工作做铺垫。

• Theory has a separate entry, covering the chirality phenomenon and optical activity at the level of principle rather than of application.理论另有一条，讲手性现象与光学活性在原理层面的问题，不停在应用上。

• Chiral supramolecular chemistry and chirality on the nanoscale close the physical strand, near the spectroscopic work the journal already carries.手性超分子化学与纳米尺度手性收束物理方向，与刊物已有的光谱学工作贴得很近。

• Pharmacokinetics and pharmacodynamics of chiral drugs are handled together, from absorption, distribution, protein binding and biotransformation through to receptor interactions and toxicological activity.手性药物的药代与药效合并受理，从吸收、分布与蛋白结合走到生物转化，再延伸到受体作用与毒理活性。

• Clinical pharmacology is listed separately, with therapeutic index and response, bioavailability, adverse drug reactions and drug-drug interactions under it.临床药理学单列，治疗指数与疗效反应、生物利用度在其条目之内，不良反应与药物相互作用也在其中。

• Regulatory and legal aspects in the development, testing and marketing of chiral compounds are in scope, which puts approval practice beside bench work.手性化合物在开发、检验与上市环节的监管与法律问题同样在范围内，审批实务因此与实验台并排。

• Stereochemistry of pesticides and other xenobiotics ends the list, bringing environmental and agrochemical samples into a journal built around molecules.农药与其他外源物的立体化学排在末尾，把环境样品与农化样品带进这本围绕分子办起来的刊物。

• Beyond full papers the journal takes brief reviews, short communications, tutorials, conference reports and book reviews, a set that keeps every format short.除常规论文外，刊物还收简报式综述与短通讯，也收教程、会议报告与书评，每一种体裁都压在短的一侧。

• The readership named by the editors is organic, medicinal and biological chemists, with pharmacologists and toxicologists alongside, an audience that reads synthesis, analysis and biology together.编辑部点明的读者是有机化学家、药物化学家与生物化学家，药理学家与毒理学家也在其中，这批人把合成、分析与生物学放在一起读。

History

• The first volume appeared in 1989, published from New York by John Wiley & Sons, and the title has not missed a year since.第 1 卷于 1989 年问世，由 John Wiley & Sons 在纽约出版，此后每年都没有落空。

• That launch volume carried a masthead listing the editorial board, which shows the journal was built as a standing publication from the start.创刊卷附有刊头页，上面列出编委会名单，可见它从最初就按常设刊物搭建。

• Volume numbering has never restarted, so 1989 is volume 1 and the volume running through 2026 is 38.卷号从未重新起算，1989 年是第 1 卷，贯穿 2026 年的一卷是第 38 卷。

• Two ISSNs have run in parallel, 0899-0042 for the print edition and 1520-636X for the electronic one, with Coden CHRLEP and LCCN 89646700.两个刊号长期并行，印刷版是 0899-0042，电子版是 1520-636X，另有 Coden 号 CHRLEP 与 LCCN 89646700。

• Print issues ceased with 2013, and everything published after that date lives only in the online edition.印刷版止于 2013 年，此后发表的内容只存在于网络版。

• Ten issues a year was the pattern for a long stretch, and the National Library of Medicine still records that figure from 1998 onward.每年 10 期曾经维持了很长一段，美国国家医学图书馆（National Library of Medicine）至今按 1998 年以来的旧例记录这个数字。

• The record now lags behind, since volume 37 ran Issues 1 to 12 across 2025 and volume 38 had reached Issue 11 by late October 2026.这条记录已经落后，2025 年第 37 卷出满第 1 至第 12 期，2026 年第 38 卷到 10 月下旬已见第 11 期。

• Twelve issues to a volume is the working rhythm, and the journal still closes one volume per calendar year.一卷 12 期是眼下的节奏，每年仍旧收束一卷。

• MEDLINE has covered the journal from volume 1, number 1 in 1989 without interruption, and the same span carries into PubMed.MEDLINE 自 1989 年第 1 卷第 1 期起连续收录，同一跨度延续到 PubMed。

• Its MeSH headings are Isomerism and Molecular Conformation, and the title belongs to the Index Medicus subset.主题词定为 Isomerism 与 Molecular Conformation，刊物同时被列入 Index Medicus 选目。

• Science Citation Index Expanded indexes it, and Journal Citation Reports files it under organic, analytical, medicinal and pharmacology categories, organic leading at 25 of 58.科学引文索引扩展版收录本刊，期刊引证报告把它归入四个类目，有机化学与分析化学各占一类，药物化学与药理学另占两类，有机一类位置最高，58 种刊中列第 25。

• The 2025 Journal Impact Factor is 2.4 against a five-year value of 2.2, and a cited half-life of 9.9 years shows the older papers still being read.2025 年影响因子 2.4，五年影响因子 2.2，被引半衰期 9.9 年，早年论文仍有人在读。

• Access is hybrid, so an author may open a single article under CC BY, CC BY-NC or CC BY-NC-ND while the rest of the content stays behind a subscription.访问模式为混合开放获取，作者可以把单篇按 CC BY 系列许可开放，另有 CC BY-NC 与 CC BY-NC-ND 两档，其余内容依旧订阅。

• The 2025 measures put acceptance at 43 percent and the median wait for a first decision at 30 days.2025 年的数字是录用率 43%，投稿到首次决定的中位时间 30 天。

Editors

• Minghua Liu is Editor, working from the Institute of Chemistry of the Chinese Academy of Sciences in Beijing.主编为（Minghua Liu），工作单位是中国科学院化学研究所（北京）。

• His research runs through supramolecular chirality and chiral self-assembly, territory the journal covers under its supramolecular heading.他的研究集中在超分子手性与手性自组装，正是刊物超分子条目覆盖的地带。

• Simona Collina of the pharmaceutical sciences department at the University of Pavia is one of three associate editors.帕维亚大学（Università di Pavia）药物科学系的（Simona Collina）是三位副编辑之一。

• The other two are Gennaro Pescitelli, from the chemistry department at the University of Pisa, and Oliver Trapp, from the chemistry department at Ludwig-Maximilians-Universität München.另两位是比萨大学（University of Pisa）化学系的（Gennaro Pescitelli）与慕尼黑大学（Ludwig-Maximilians-Universität München）化学系的（Oliver Trapp）。

• Two editors emeriti remain on the page, Nina D. Berova of Columbia University and John Caldwell of the University of Liverpool medical faculty.编委页上还留着两位荣休编辑，哥伦比亚大学（Columbia University）的（Nina D. Berova）与利物浦大学（University of Liverpool）医学院的（John Caldwell）。

• Fifty-eight people sit on the editorial board, alphabetically from Sergio Abbate at Brescia to Francesco Zinna at Pisa.编委会共 58 人，按字母顺序排，首位是布雷西亚大学（Università di Brescia）的（Sergio Abbate），末位是比萨大学的（Francesco Zinna）。

• Board members come from Europe, Asia and North America, with the United States the most heavily represented, Italy and China next, and Germany and Japan also holding several seats each.编委来自欧洲、亚洲与北美，美国的人数最多，意大利与中国次之，德国与日本也各有多位学者。

• Canada, Israel, Australia, Poland, Hungary and Georgia are represented too, the last through Bezhan Chankvetadze at Tbilisi State University.加拿大、以色列与澳大利亚也有席位。波兰、匈牙利与格鲁吉亚同样在列，格鲁吉亚的席位由第比利斯国立大学（Tbilisi State University）的（Bezhan Chankvetadze）出任。

• Separation science is thickly represented, with Daniel W. Armstrong at Texas Arlington and Eiji Yashima at Nagoya on the list.分离科学在名单里人数可观，德克萨斯大学阿灵顿分校（University of Texas at Arlington）的（Daniel W. Armstrong）与名古屋大学（Nagoya University）的（Eiji Yashima）都在其中。

• Chiroptical work brings in Laurence A. Nafie at Syracuse, Prasad Polavarapu at Vanderbilt and Lorenzo Di Bari at Pisa.手性光谱方面有锡拉丘兹大学（Syracuse University）的（Laurence A. Nafie）、范德堡大学（Vanderbilt University）的（Prasad Polavarapu）与比萨大学的（Lorenzo Di Bari）。

• Synthetic and supramolecular chemists are there as well, among them Shu-Li You in Shanghai, Lutz Ackermann in Göttingen and Jerome Lacour in Geneva.合成与超分子化学家也在其列，包括上海有机所的（Shu-Li You）、哥廷根大学的（Lutz Ackermann）与日内瓦大学的（Jerome Lacour）。

• Industry has two seats, Zach Breitbach at AbbVie and Christopher J. Welch at Welch Innovation, which keeps method transfer part of the conversation.产业界占两个席位，艾伯维（AbbVie）的（Zach Breitbach）与 Welch Innovation 的（Christopher J. Welch），方法转移因此留在讨论中。

• The page names no section editors, so one editor, three associates, two emeriti and the board carry the whole subject spread.页面上没有分区编辑，一位主编与三位副编辑挑大梁，两位荣休编辑与编委会补位。