Cell Calcium is a peer-reviewed scientific journal covering the physiological and pathological roles of calcium and related ions in biological systems.《细胞钙》(Cell Calcium)是一本涵盖钙离子及相关离子在生物系统中生理与病理作用的同行评审科学期刊。
The journal is published by Elsevier and was established in 1980.该期刊由爱思唯尔出版,创刊于1980年。
Its publication scope includes original research articles, short communications, and review articles.其出版内容涵盖原创研究论文、快报以及综述文章。
The journal focuses on interdisciplinary research involving calcium as a second messenger.该期刊聚焦于钙作为第二信使的跨学科研究。
Key research areas include cell signaling, the biophysics of calcium pumps and ion channels, intracellular calcium store dynamics, and mitochondrial calcium handling mechanisms.主要涉及的研究领域包括细胞信号转导、钙泵与离子通道生物物理学、细胞内钙库动态以及线粒体钙处理机制。
The journal also highlights mechanistic studies on aberrant calcium homeostasis in pathological conditions such as neurodegeneration, cardiac disease, muscular dystrophy, and cancer.期刊同时关注异常钙稳态在神经退行性疾病、心脏病、肌肉萎缩和癌症等病理状态中的机制研究。
Additionally, the development of fluorescent indicators and advanced imaging techniques for tracking real-time calcium dynamics remains an important focus.此外,用于实时检测细胞内钙离子动态的荧光探针及成像技术的发展也是其重点关注方向。
Cell Calcium was established in 1980 by Churchill Livingstone to provide a dedicated forum for the rapidly expanding calcium signaling research community.《细胞钙》于1980年由丘吉尔·利文斯通(Churchill Livingstone)出版社创刊,旨在为迅速发展的钙信号研究群体提供专门的学术论坛。
Following Elsevier's acquisition of Churchill Livingstone's parent company, the publication of the journal transitioned to Elsevier.随着爱思唯尔对丘吉尔·利文斯通母公司的收购,该期刊转入爱思唯尔旗下出版。
Over the subsequent decades, the journal tracked major breakthroughs in calcium transduction, including the identification of inositol trisphosphate receptors and store-operated calcium entry machinery.在随后的数十年中,该期刊持续追踪了钙信号转导研究的重要突破,包括三磷酸肌醇受体的鉴定以及钙库操纵性钙内流分子的发现。
The journal regularly publishes themed special issues focusing on frontier topics in calcium signaling, fostering international scientific dialogue.期刊经常推出聚焦特定钙信号前沿的主题特刊,促进了该领域的国际学术交流。
Biochemists Robert H. Michell and Anthony K. Campbell served as the founding editors-in-chief of the journal.生物化学家罗伯特·H·米什勒(Robert H. Michell)和安东尼·K·坎贝尔(Anthony K. Campbell)是该期刊的创刊主编。
Subsequently, Sir Michael J. Berridge of the University of Cambridge Department of Pharmacology assumed the role of editor-in-chief, further solidifying the journal's standing in second-messenger research.随后,剑桥大学药理学系的研究员迈克尔·J·贝里奇(Michael J. Berridge)爵士接任主编,进一步确立了该期刊在第二信使研究领域的学术地位。
Subsequent editors-in-chief have included prominent calcium researchers such as James W. Putney Jr.历任主编还包括约翰·W·帕特尼(James W. Putney Jr.)等知名钙信号研究学者。
The current editorial leadership is composed of senior molecular biologists and physiologists, supported by an international editorial board spanning ion channels, cellular physiology, and pharmacology.当前编辑团队由资深分子生物学家与生理学家领衔,并由涵盖离子通道、细胞生理及药理学领域的国际编辑委员会共同支持。