Bioorganic Chemistry

Bioorganic Chemistry is a peer-reviewed journal published by Elsevier under its Academic Press imprint, founded in 1971 and devoted to chemistry at the interface between organic chemistry and biology, with a 2025 Journal Impact Factor of 5.1.《生物有机化学》（Bioorganic Chemistry）由（Elsevier）以（Academic Press）品牌出版，1971 年创刊，专注有机化学与生物学交界处的化学问题，2025 年期刊影响因子为 5.1。

Scope

• Manuscripts must address biological questions at the molecular level using organic chemistry and the principles of physical organic chemistry, rather than report synthesis for its own sake.稿件须以有机化学与物理有机化学原理，在分子层面回答生物学问题，而非单纯报告合成工作。
• Enzyme catalysis, biotransformation and enzyme inhibition form one of the journal's oldest strengths.酶催化、生物转化与酶抑制是本刊历史最久的强项之一。
• Nucleic acid chemistry and medicinal chemistry, including the design and mechanism of bioactive small molecules.核酸化学与药物化学，包括生物活性小分子的设计与作用机制。
• Natural product chemistry, natural product synthesis and biosynthesis, and antimicrobial agents.天然产物化学、天然产物合成与生物合成，以及抗菌剂。
• Lipid chemistry, peptide chemistry and biophysical chemistry of biomolecular systems.脂质化学、肽化学，以及生物分子体系的生物物理化学。
• Biological probes, bio-orthogonal chemistry and biomimetic chemistry, including labelling and imaging tools.生物探针、生物正交化学与仿生化学，包括标记与成像工具。
• For synthetic bioactive compounds the molecular target must be known and shown experimentally, docking work needs experimental support, and purely theoretical or computational manuscripts are not considered.对合成生物活性化合物，须已知分子靶标并以实验加以证明；对接研究须有实验数据支撑，纯理论或纯计算的稿件不予受理。

History

• The journal was founded in 1971 by Academic Press, and its first volume opened with a combined issue 1-2 dated September 1971.本刊由（Academic Press）于 1971 年创办，第 1 卷以 1971 年 9 月出版的第 1 至 2 期合刊开篇。
• Academic Press was absorbed into Elsevier, which still publishes the title under that imprint and distributes it on ScienceDirect.（Academic Press）后并入（Elsevier），本刊至今仍以该品牌出版，并在（ScienceDirect）平台发行。
• Output is organised in volumes that appear at roughly monthly intervals, with twelve volumes in most recent years and fourteen in 2025.刊物按卷组织，大体每月一卷，近年多为每年十二卷，2025 年为十四卷。
• The journal is subscription based with an open access option, which Elsevier describes as supporting open access.本刊以订阅为主并提供开放获取选项，（Elsevier）将其标注为支持开放获取。
• It is indexed in SCIE and Scopus, and in PubMed through MEDLINE, which has recorded several thousand of its papers.本刊被（SCIE）与（Scopus）收录，并经（MEDLINE）进入（PubMed），后者已收录其数千篇论文。
• The 2025 Journal Impact Factor is 5.1, after 4.7 in 2024, 5.307 in 2022 and 5.275 in 2021, ranking fourth of 58 in organic chemistry at Q1 while sitting in Q2 of biochemistry and molecular biology.2025 年期刊影响因子为 5.1，2024 年为 4.7，2022 年为 5.307，2021 年为 5.275；在有机化学类别位列 Q1，排名 4/58，在生化与分子生物学类别为 Q2。

Editors

• Mark D. Distefano of the University of Minnesota Twin Cities is editor-in-chief, with research interests in chemical biology, bioorganic chemistry and protein engineering.主编为明尼苏达大学双城分校的（Mark D. Distefano），研究兴趣包括化学生物学、生物有机化学与蛋白质工程。
• A group of editors handles manuscripts, among them Silvia Schenone of the University of Genoa for medicinal chemistry, Jumi A. Shin of the University of Toronto and Maria Emilia Sousa of the University of Porto.稿件由一组编辑分工处理，其中包括热那亚大学负责药物化学的（Silvia Schenone）、多伦多大学的（Jumi A. Shin）与波尔图大学的（Maria Emilia Sousa）。
• Others include Tanaji Talele of St John's University and Kurt Deshayes, while the board also carries Gang Xu of the Kunming Institute of Botany at the Chinese Academy of Sciences and Wen-Bin Zhang of Peking University.其他编辑包括圣约翰大学的（Tanaji Talele）与（Kurt Deshayes），编委中还有中国科学院昆明植物研究所的（Gang Xu）与北京大学的（Wen-Bin Zhang）。
• About thirty board members from thirteen countries serve, with the United States, China, Canada, Italy and South Korea the largest contingents.编委会约三十人，来自十三个国家，其中美国、中国、加拿大、意大利与韩国人数最多。
• The journal publishes regular articles, short communications and reviews, with reviews normally invited and unsolicited proposals needing prior agreement from an editor or board member.本刊发表常规论文、短通讯与综述，综述通常为约稿，非约稿综述须事先征得编辑或编委同意。
• Each member's affiliation and declared research interests are published with the board list, so authors can identify a suitable handling editor, and thematic article collections are listed separately on the journal site.编辑部随编委名单公布各位成员的单位与研究方向，作者可据此选定合适的处理编辑；专题文集则在期刊网站上单独列出。