Bioinformatics

Bioinformatics is a fully open access journal published by Oxford University Press for the International Society for Computational Biology that began as CABIOS in 1985, with a 2025 Journal Impact Factor of 5.5.《生物信息学》（Bioinformatics）由（Oxford University Press）为国际计算生物学学会出版，为完全开放获取期刊，1985 年以（CABIOS）之名创刊，2025 年影响因子为 5.5。

Scope

• The journal publishes new developments in genome bioinformatics and computational biology, with emphasis on algorithms and databases that advance biomedical research.本刊发表基因组生物信息学与计算生物学的新进展，侧重能推进生物医学研究的算法与数据库。
• Sequence analysis, alignment, assembly and the interpretation of high-throughput sequencing data are central subjects.序列分析、比对、组装以及对高通量测序数据的解读是核心主题。
• Structural bioinformatics, including protein structure prediction and molecular simulation, forms a further strand.结构生物信息学，包括蛋白质结构预测与分子模拟，构成另一条主线。
• Gene and protein expression analysis, phylogenetics and systems-level modelling are within scope.基因与蛋白表达分析、系统发生学以及系统层面的建模均在其范围之内。
• Databases, ontologies and data resources are treated as publishable contributions in their own right.数据库、本体与数据资源本身即被视为可发表的研究贡献。
• Two shorter sections, Discovery Notes and Application Notes, publish biologically interesting findings and novel software tools.（Discovery Notes）与（Application Notes）两个短篇栏目，发表有生物学意义的发现与新颖的软件工具。
• Methodological rigour, reproducibility and the availability of source code and data are emphasised in assessment.评审强调方法学的严谨性、可复现性，以及源代码与数据的可获得性。

History

• The journal was established in 1985 as Computer Applications in the Biosciences, with Robert J. Beynon as its founding editor.本刊于 1985 年以（Computer Applications in the Biosciences）之名创办，创始主编为 Robert J. Beynon。
• It took its present name, Bioinformatics, in 1998, when an online edition was also introduced.1998 年，本刊改用现名（Bioinformatics），并同时推出在线版本。
• It is an official journal of the International Society for Computational Biology, a role it resumed in 2009 after an interruption.本刊是国际计算生物学学会的官方期刊，该身份在中断后于 2009 年恢复。
• Editors over the years have included Chris Sander, Gary Stormo, Christos Ouzounis, Martin Bishop and Alex Bateman before the current pair took office.历任主编包括 Chris Sander、Gary Stormo、Christos Ouzounis、Martin Bishop 与 Alex Bateman，此后由现任两位主编接任。
• The journal moved to a fully open access model, and it now publishes on a biweekly schedule.本刊转为完全开放获取模式，目前以双周刊的频率出版。
• Its impact factor stood at 6.937 in 2021 and 5.5 in 2025, with the title placed in the first quartile of its category.其影响因子在 2021 年为 6.937，2025 年为 5.5，本刊位列所在类别第一分区。

Editors

• Alfonso Valencia, of the Barcelona Supercomputing Center, and Janet Kelso, of the Max Planck Institute for Evolutionary Anthropology, are the editors-in-chief.巴塞罗那超级计算中心的 Alfonso Valencia 与（Max Planck Institute for Evolutionary Anthropology）的 Janet Kelso 担任主编。
• The editorial structure includes editors for genome analysis, sequence analysis, structural bioinformatics, phylogenetics and systems biology.编辑架构包含基因组分析、序列分析、结构生物信息学、系统发生学与系统生物学等方向的编辑。
• Manuscripts are peer reviewed, and the journal requires that software be available and that claims be reproducible.稿件经同行评审，本刊要求软件可获取、结论可复现。
• Because the journal is fully open access, accepted papers are free to read, and an article processing charge applies to authors.由于本刊为完全开放获取，录用论文可免费阅读，作者须支付文章处理费。
• The journal runs a conference proceedings programme alongside the regular issues, in partnership with the society.本刊与学会合作，在正刊之外还出版会议论文集。
• Authors are encouraged to deposit code and data in public repositories and to follow community reproducibility standards.鼓励作者把代码与数据存入公共仓库，并遵循学界的可复现性标准。