Biochemical Genetics

Biochemical Genetics is a peer-reviewed journal from Springer US in New York, founded in 1967 and given to the biochemical principles behind genome structure, expression and evolution in all organisms.《生物化学遗传学》是 Springer US 在纽约出版的同行评审期刊，1967 年创刊，专门讨论一切生物的基因组结构、表达与进化背后的生化原理。

Clarivate put its 2025 Journal Impact Factor at 1.9, against a five-year value of 2.0, and ranked it 140th among 192 titles in genetics and heredity.Clarivate 记录的 2025 年影响因子为 1.9，五年影响因子为 2.0，在遗传与遗传学类目 192 种期刊中列第 140 位。

Scope

• The remit is stated biochemically, and the journal asks for the chemistry that governs how a genome is organised, how it is read and how it changes over time.刊物把范围写在生化层面，要求稿件处理支配基因组如何组织、如何读取与如何随时间改变的那套化学。

• Pure and applied work are admitted on equal terms, and the organisms studied run from viruses and microbes to crop plants, farm animals and people.纯基础与应用两类工作被同等接收，研究对象从病毒与微生物一直延伸到作物、家畜与人。

• Genomics heads the list of named topics, taking in the structure, content and comparative analysis of whole genomes.基因组学在点名的方向中排在首位，涵盖全基因组的结构、组成与比较分析。

• Proteomics follows, with the inventory, modification and interaction of proteins treated as a genetic question and not as an exercise in cataloguing.蛋白质组学紧随其后，蛋白质的组成、修饰与相互作用被当作遗传学问题，而非编目式的清点。

• Population genetics appears in both theoretical and empirical dress, from models of allele frequency to surveys of natural stands and local breeds.群体遗传学以理论与实证两种面貌出现，从等位基因频率模型到天然居群与地方品种的调查。

• Phylogenetics and phylogeography have a place, because the reconstruction of relationships among lineages rests on sequence and biochemical variation.系统发育学与谱系地理学占有一席之地，谱系关系的重建本就依托序列与生化层面的变异。

• Metagenomics is named outright, and microbial genetics beside it, which keeps environmental sequencing and the genetics of bacteria and archaea inside the door.宏基因组学被直接点名，微生物遗传学并列其侧，环境测序与细菌、古菌的遗传研究因此留在门内。

• The genetics and evolution of wild and cultivated plants form a long strand, covering landraces, breeding lines and their wild relatives.野生植物与栽培植物的遗传和进化是一条长线，地方品种、育种品系及其野生近缘种都在其中。

• Animal genetics and evolution are treated on the same footing, with farm species, model organisms and free-living populations all admissible.动物遗传与进化得到同样对待，家养物种、模式生物与野生种群都可以投。

• Human genetics and evolution occupy ground of their own, from population history and adaptation to the inheritance of complex traits.人类遗传与进化自成一格，从群体历史与适应性演化到复杂性状的遗传都在其列。

• Genetic disease and the genetic markers of disease are named among the topics, so association studies and diagnostic marker work sit within the remit.遗传性疾病与疾病的遗传标记列入选题，关联研究与诊断标记的工作因此落在范围之内。

• Gene technology and gene therapy are admitted, vector design and editing tools included, together with the preclinical testing that precedes a clinical programme.基因技术与基因治疗同样接收，载体设计与编辑工具包括在内，临床计划之前的临床前验证也算。

• Experimental and analytical methods count as a category in their own right, provided a new technique is set out fully and compared with established practice.实验方法与分析方法自成类别，前提是新技术交代完整并与既有做法逐项比对。

• Statistical and computational methods are welcomed alongside them, which reflects how much of the field is now settled at the keyboard rather than the bench.统计方法与计算方法与之并列，领域内相当一部分结论如今在键盘前而非实验台上定下。

• A clear scientific hypothesis is required throughout, and every manuscript is expected to address a broad scientific audience rather than a narrow specialist one.明确的科学假设贯穿始终，每篇稿件都要求面向较宽的学术读者，而非狭小的专业圈子。

History

• The first issue carried the date June 1967, volume 1 number 1, and the publisher was Plenum Press of New York.创刊号标注 1967 年 6 月，为第 1 卷第 1 期，出版者是纽约的 Plenum Press。

• Its founding description offered the journal as a link between biology, chemistry and genetics, a forum for the biochemical genetics of organisms from viruses to man.创刊说明把刊物呈现为生物学、化学与遗传学之间的连接，讨论从病毒到人的生化遗传学的论坛。

• Volumes came quickly at the start, three of them in 1973 alone, and only from 1975 did the count settle at one a year.早期卷次出得很密，仅 1973 年就有三卷，直到 1975 年才稳定为每年一卷。

• Numbering has been mechanical since then, volume 13 in 1975 and volume 64 in 2026, so a volume number can be read off the year.此后编号沿用固定算法，1975 年为第 13 卷，2026 年为第 64 卷，卷号可由年份直接算出。

• For most of the print era twelve numbers a year were bound as six combined issues, running 1-2, 3-4 and onward to 11-12.印刷时代的大部分年份把每年 12 个期号合订为 6 册，编号为 1-2、3-4，直到 11-12。

• That arrangement held from volume 15 in 1977 to volume 52 in 2014, and the National Library of Medicine still records a frequency of twelve numbers a year.这一形制从 1977 年第 15 卷延续到 2014 年第 52 卷，美国国家医学图书馆至今仍记其频率为每年 12 期。

• The imprint passed in 1999 to Kluwer Academic/Plenum Publishers, a joint name that recorded the absorption of Plenum into Kluwer Academic.1999 年版权页改记 Kluwer Academic/Plenum Publishers，这个双名记录了 Plenum 并入 Kluwer Academic 一事。

• Kluwer Academic itself joined Springer in 2004, and the publisher line has carried both names since, as SPRINGER/PLENUM PUBLISHERS.Kluwer Academic 于 2004 年并入 Springer，此后出版者栏一直把两个名字并写为 SPRINGER/PLENUM PUBLISHERS。

• The New York address survived both mergers, and the title is issued today from Springer's office at 233 Spring Street.纽约这个地址在两次合并中都留了下来，刊物现由 Springer 设在 Spring Street 233 号的办公室出版。

• An electronic edition followed the printed one under ISSN 1573-4927, and the National Library of Medicine notes that the journal is also issued online.电子版在印刷版之后出现，刊号为 1573-4927，美国国家医学图书馆注明该刊同时以在线形式发行。

• Single-numbered issues began with volume 54 in 2016, and from volume 57 in 2019 each volume has held six of them and nothing else.单号期自 2016 年第 54 卷起出现，到 2019 年第 57 卷时每卷只含 6 个单号期。

• Access remains subscription-based with an open option attached, and Clarivate counted 10.81 per cent of the 2025 output as gold open access.阅读仍以订阅为主并另设开放选项，Clarivate 记录 2025 年载文中有 10.81% 为金色开放获取。

• The impact factor went from 1.89 in 2021 to 2.22 in 2022, held near 2.1 in 2023, dropped to 1.6 in 2024 and recovered to 1.9 in 2025.影响因子 2021 年为 1.89，2022 年升至 2.22，2023 年维持在 2.1，2024 年落到 1.6，2025 年回到 1.9。

• Output is heavy for a specialist title, 268 articles in the 2025 count, while 3001 citations and a cited half-life of 3.5 years point to a fast-turning literature.对一本专业刊物来说载文量偏重，2025 年计 268 篇，总被引 3001 次与被引半衰期 3.5 年指向一份更替较快的文献。

• The 2025 assessment gave a JCI of 0.43 and a percentile of 27.3, fourth quartile in biochemistry and molecular biology, third in genetics and heredity.2025 年评估给出 JCI 0.43 与百分位 27.3，在生化与分子生物学类目列第四档，在遗传与遗传学类目列第三档。

Editors

• The journal calls its contents peer-reviewed articles, so nothing is accepted on an editor's say-so alone.刊物把自己的内容称作同行评审论文，稿件不会仅凭编辑的一句话录用。

• Assessment rests on the hypothesis and on whether the sampling or experimental design can carry the conclusion drawn from it.评判落在假设本身，以及取样设计或实验设计能否撑起由它得出的结论。

• Statistical treatment is examined separately, and a paper whose analysis cannot bear its claim goes back even when the data look promising.统计分析单列出来审，分析撑不住结论的稿件即使数据看上去有戏也会退回。

• Pseudoreplication is named among the grounds for rejection, a test aimed at designs where replicates share one treatment unit.伪重复被点名为退稿理由之一，这一条专拦重复单元共用同一处理的设计。

• Work on a single region or a single organism is read on its merits, provided the result answers a question larger than the case.单一地区或单一生物的研究按本身价值衡量，前提是结果回应的问题大于个案。

• Review articles form a separate category, and the editors ask for a systematic analysis of the field or a meta-analysis instead of an annotated reading list.综述自成类别，编辑部索要的是对领域的系统分析或一次荟萃分析，而非带注解的阅读清单。

• Method papers face an added demand, since a new protocol or pipeline must be set against the established method it hopes to displace.方法类稿件多一道要求，新流程须与它想取代的既有方法正面对照。

• The editorial office is at 233 Spring Street in New York, and manuscripts travel through the publisher's online submission system.编辑部设在纽约 Spring Street 233 号，稿件经出版方的在线投稿系统流转。

• Business with the handling editor is conducted in English, which is also the only language in which the journal publishes.与责任编辑的往来用英文进行，英文也是刊物唯一使用的出版语言。

• Board coverage follows the scope, so a submission on plant breeding and one on human disease are not handed to the same reader.编委的学科覆盖随范围而定，植物育种与人类疾病的稿件不会交给同一位读者。