Archives of Toxicology

Archives of Toxicology (commonly abbreviated as ''Arch. Toxicol.') is a peer-reviewed monthly academic journal in toxicology published by Springer. It carries research on the toxicological and pathophysiological mechanisms by which chemicals act on human and mammalian cells and organisms, in the form of short communications, reviews, original articles and commentaries.Archives of Toxicology（常用缩写 Arch. Toxicol.）是由施普林格（Springer）出版的毒理学领域同行评审学术月刊，刊载关于化学物质作用于人体与哺乳动物细胞及机体方式的毒理学与病理生理机制研究，稿件类型包括短讯、综述、原创论文与评论。

Scope

According to the aims published by the publisher, the journal aims to promote understanding of toxicological and pathophysiological mechanisms relevant to the mode of action of chemicals on human and mammalian cells and organisms. Short communications, reviews, original articles and commentaries are particularly welcome when they focus on molecular mechanisms of toxic substances, in vitro techniques for toxicity testing and regulatory toxicology, advances in omics techniques for the identification and classification of toxic substances, and the mechanisms and relevance of metabolic activation and inactivation.根据出版商公布的办刊宗旨，该刊旨在增进对毒理学机制与病理生理机制的理解，这些机制与化学物质作用于人体及哺乳动物细胞和机体的方式相关；特别欢迎以毒物分子机制、体外毒性测试与法规毒理学技术、组学技术在毒物识别与分类中的应用，以及代谢活化与失活机制及相关性为关注重点的短讯、综述、原创论文与评论。^[1]

• Molecular mechanisms of toxic substances: explanations at the molecular level of how chemicals act on cells and organisms, forming the journal's core subject area.毒物的分子机制： 以分子水平阐释化学物质对细胞与机体的作用方式，构成本刊的核心选题。
• In vitro testing and regulatory toxicology: research on in vitro toxicity testing methods and regulatory toxicology techniques, addressing the time and cost constraints of conventional animal experiments.体外测试与法规毒理学： 刊发关于体外毒性测试方法以及法规毒理学评价技术的研究，以应对传统动物实验周期长、成本高的局限。
• Omics techniques and systems biology: the use of omics technologies to identify and classify toxic substances, together with efforts to model biological systems and quantitatively simulate perturbations caused by toxicants.组学技术与系统生物学： 关注组学技术用于毒物的识别与分类，并探讨如何对生物系统建模、以定量方式模拟毒物造成的扰动。
• Metabolic activation and inactivation: the metabolic conversion of chemicals into toxic species or their detoxification, and the relevance of these pathways to toxicity.代谢活化与失活： 关注化学物质在体内被代谢活化为毒性形态或被代谢失活的过程，及其与毒性的相关性。
• Analysis, toxicokinetics and forensic toxicology: new developments in the analytical detection of toxicants, in toxicokinetics and in forensic toxicology, alongside a letters-to-the-editor forum for discussion.分析、毒代动力学与法医毒理学： 覆盖毒物分析检测方法、毒代动力学以及法医毒理学领域的新进展，另设供讨论的致编辑论坛。

The journal's orientation is thus clearly defined, resting on mechanistic research rather than on the catalogue of findings. The publisher notes directly in its aims that toxicology faces two major challenges, namely insufficient available toxicological data and the need to keep pace with rapidly growing knowledge of molecular mechanisms, and these form the starting point of its editorial selection.该刊的定位因此十分明确，它以机制研究而非结果罗列为重心；出版方在办刊宗旨中直接指出当前毒理学面临的两大困难，即可用毒理数据不足以及必须跟上分子机制知识的快速增长，这也构成了其选题取向的出发点。

History

• 1930: the journal was founded under its German title Sammlung von Vergiftungsfällen, a compilation of poisoning cases.1930年： 以德文刊名 Sammlung von Vergiftungsfällen（中毒案例集）创刊，属案例汇编性质的出版物。
• 1954: it was renamed Archiv für Toxikologie, gradually shifting from a compilation of cases to an academic journal centred on experimental toxicology.1954年： 更名为 Archiv für Toxikologie，由案例汇编逐步转变为以实验毒理学研究为主的学术期刊。
• 1974: the journal adopted its present title Archives of Toxicology and switched to publication in English.1974年： 改用现名 Archives of Toxicology，并转为英文出版。
• 1930 to present: the journal has been published by Springer in Germany throughout, now appearing monthly, with print ISSN 0340-5761, electronic ISSN 1432-0738 and manuscripts handled through an editorial management platform.1930年至今： 一直由施普林格（Springer）在德国出版，现为月刊，纸质版 ISSN 为 0340-5761，电子版 ISSN 为 1432-0738，投稿系统为编辑部管理平台。
• Indexing and ranking: the journal is indexed in SCIE, classified in JCR under toxicology in the Q1 quartile, with an impact factor of 10.9 in 2025. In the Chinese Academy of Sciences journal ranking it places in the second tier of medicine and the first tier of toxicology, and the latest assessment records no warning.收录与分区： 该刊被 SCIE（科学引文索引扩展版）收录，JCR 学科分类为毒理学，位列 Q1，2025 年影响因子为 10.9，在中国科学院期刊分区中位于医学 2 区、毒理学 1 区，最新评估未见预警记录。

Editors

The journal has one Editor-in-Chief, a Deputy Editor-in-Chief and a number of Associate Editors. Manuscripts are peer-reviewed, with final acceptance decided by the Editor-in-Chief, and the editorial office is closely affiliated with the Leibniz Research Centre for Working Environment and Human Factors in Germany.期刊设主编（Editor-in-Chief）一人，另设副主编一人及多名副主编（Associate Editor），稿件经同行评审后由主编决定录用；编辑部与莱布尼茨工作环境与人类因素研究中心（德国）关系密切。

• Jan G. Hengstler is the current Editor-in-Chief, based at the Leibniz Research Centre for Working Environment and Human Factors in Germany, and is responsible for the journal's overall academic direction and acceptance decisions.Jan G. Hengstler：现任主编，供职于莱布尼茨工作环境与人类因素研究中心（德国），负责期刊的整体学术方向与录用决策。
• Hermann M. Bolt is the Deputy Editor-in-Chief and likewise works at the Leibniz Research Centre for Working Environment and Human Factors in Germany, assisting with day-to-day editorial business.Hermann M. Bolt：副主编，同样任职于莱布尼茨工作环境与人类因素研究中心（德国），协助主编处理日常编辑事务。
• The Associate Editors form an international team: the list includes Michael Arand of the University of Zurich in Switzerland, Guorui Liu of Zhejiang Normal University in China, Paul Jennings of the Vrije Universiteit Amsterdam in the Netherlands, and Mathieu Vinken of the Vrije Universiteit Brussel in Belgium.副主编构成跨国团队： 名单中包括来自苏黎世大学（瑞士）的 Michael Arand、来自浙江师范大学（中国）的 Guorui Liu、来自阿姆斯特丹自由大学（荷兰）的 Paul Jennings，以及来自鲁汶自由大学（比利时）的 Mathieu Vinken。
• The full editorial board and recent board changes are listed on the journal's official website.完整编委会名单与近期编委变动见期刊官网。^[2]