Antioxidants & Redox Signaling

Antioxidants & Redox Signaling (commonly abbreviated as Antioxid. Redox Signal.) is a peer-reviewed journal published by Mary Ann Liebert, founded in the United States in 1999 and issued thirty-six times a year. It is the most frequently published specialist title in redox biology and medicine, concentrating on the part played by redox signalling in physiology and pathology.《抗氧化剂与氧化还原信号》（Antioxidants & Redox Signaling，常用缩写为 Antioxid. Redox Signal.）是由玛丽·安·利伯特出版社出版的同行评审学术期刊，1999 年创刊于美国，每年出版三十六期。该刊是氧化还原生物学与医学领域出版频率最高的专业刊物，专注氧化还原信号转导在生理与病理过程中的作用。

Scope

Antioxidants & Redox Signaling treats redox as a language rather than a catalogue of toxicities, asking papers to show how redox change is relayed through signalling networks instead of reporting only end-points of oxidative damage. Its principal subject areas include:Antioxidants & Redox Signaling 的取稿立场是把氧化还原状态看作一门语言而非一组毒性，要求论文说清氧化还原变化如何在信号网络中传递，而非仅报告氧化损伤的终点事件。收文范围覆盖的主要方向包括：

• Redox signalling: signalling functions of reactive oxygen and nitrogen species, cysteine redox modifications, and redox-sensitive transcription factor pathways.氧化还原信号转导： 活性氧与活性氮的信号功能、半胱氨酸氧化还原修饰、氧化还原敏感的转录因子通路。
• Nitric oxide and gasotransmitters: nitric oxide synthases and their products, signalling by hydrogen sulfide and carbon monoxide, and cross-regulation between gasotransmitters and redox.一氧化氮与气体信使： 一氧化氮合酶及其产物、硫化氢与一氧化碳的信号作用、气体信使与氧化还原状态的交叉调控。
• Antioxidant systems: glutathione and thioredoxin systems, superoxide dismutase families, and transcriptional control of antioxidant defence.抗氧化系统： 谷胱甘肽与硫氧还蛋白系统、超氧化物歧化酶家族、抗氧化防御的转录调控。
• Oxidative stress in disease: cardiovascular and metabolic disease, neurodegeneration and cancer, and redox imbalance in inflammation and immunity.疾病中的氧化应激： 心血管与代谢性疾病、神经退行性疾病与肿瘤、炎症与免疫中的氧化还原失衡。
• Methodology: redox probes and live imaging, redox proteomics, and increasingly their combination with metabolic flux analysis.方法学： 氧化还原探针与活体成像、氧化还原蛋白质组学、及其与代谢通量分析的结合。

Research articles and comprehensive reviews predominate, joined by viewpoints, editorials and forward looks, and requirements governing redox terminology and assays are set out in the author guidance.稿件类型以研究论文与大型综述为主，另设观点、社论与前瞻评论，并把氧化还原相关术语与检测方法的规范要求写入了投稿说明。

History

• Founding (1999): the journal opened with volume 1 number 1 in spring 1999, a product of redox biology coming into its own in the late 1990s.创刊（1999年）： 本刊于 1999 年春季以第 1 卷第 1 期创刊，是氧化还原生物学在二十世纪九十年代末独立成科的产物。
• Discipline maturing: free radical medicine had accumulated quantities of fragmentary evidence through the 1990s, and this title consolidated that evidence into a discipline with its own language and quantitative methods.学科成熟： 二十世纪九十年代自由基医学积累了大量碎片证据，本刊把这些证据整合为一门有自身语言与定量方法的学科，并以此为解释框架。
• Frequency: issues were sparse at first and then steadily more frequent, fixed at thirty-six issues a year from 2013, among the highest publishing frequencies in the field.刊期演变： 本刊早年刊期较疏，其后持续加密，至 2013 年起固定为每年三十六期，是该领域出版频率最高的刊物之一。
• Metric trend: the impact factor rose from 6.5 in 2017 to 8.4 in 2020 before easing back to lie between 6 and 7 from 2022 to 2025, standing at 6.8 in 2025.指标走势： 影响因子自 2017 年的 6.5 上升至 2020 年的 8.4，其后回落并在 2022 至 2025 年间稳定于 6 至 7 之间，2025 年为 6.8。

Editors

An editor-in-chief directs the journal with a large international board, and referees span biochemistry, cell biology and clinical medicine. Manuscripts arrive online, and those concerning redox assays are asked for complete reliability data. Neither the publisher nor the board publishes an acceptance rate or review duration for the title.本刊由主编统筹并设庞大的国际编委会，评审人覆盖生物化学、细胞生物学与临床医学诸方面；稿件经在线系统投递，涉及氧化还原检测方法学的稿件会被要求给出完整的可靠性数据。出版方与编委会均未公布本刊的录用比例与审稿时长。

• Terminological discipline: the office is strict about the use of antioxidant and oxidant terms, and papers that blur the two into loosely coined notions are sent back for rewriting.术语纪律： 编辑部对「抗氧化」与「氧化」的用法要求严格，混用二者概念或以生造词表述的稿件常被要求改写。
• Method threshold: specificity of assays has been treated as a red line from the start, and papers resting solely on non-specific fluorescent probes struggle in review.方法门槛： 本刊自创刊起就把检测方法的特异性视为红线，仅以非特异性荧光探针为唯一证据的稿件难以通过评审。
• Review tradition: the journal has long carried large reviews bearing the field's periodic stock-taking, and many invited surveys have become entry reading for newcomers and practitioners alike.综述传统： 本刊长期以大篇幅综述承载领域的阶段性总结，许多邀稿综述成为新手与从业者共同的入门文献。