ALTEX-Alternatives to Animal Experimentation

ALTEX - Alternatives to Animal Experimentation is a quarterly open access journal founded in 1984 and published on behalf of CAAT and partner organisations, with a 2025 Journal Impact Factor of 5.5.《ALTEX——动物实验替代方法》（ALTEX-Alternatives to Animal Experimentation）为季刊、开放获取期刊，1984 年创办，代表（CAAT）及其伙伴机构出版，2025 年影响因子为 5.5。

Scope

• The journal is devoted to the development, validation and implementation of methods that replace, reduce or refine the use of animals in research, testing and education.本刊致力于开发、验证与实施替代、减少或优化动物用于研究、试验与教育的方法。
• New approach methodologies, including organ-on-chip systems, human cell models and in silico toxicology, are central subjects.新方法学，包括器官芯片系统、人体细胞模型与计算毒理学，是核心主题。
• Regulatory toxicology and the acceptance of non-animal methods by authorities are treated at length.监管毒理学以及监管机构对非动物方法的接受，受到重点讨论。
• Read-across, quantitative structure-activity relationships and machine learning for hazard assessment are covered.用于危害评估的交叉参照、定量构效关系与机器学习均被收录。
• The ethical and philosophical dimensions of animal use, and the welfare of laboratory animals, are addressed.动物使用涉及的伦理与哲学议题，以及实验动物福利，均有讨论。
• The journal reports on international developments, legislation and research policy for the three Rs.本刊报道国际进展、立法动向以及三 R 原则的研究政策。
• Meeting reports, commentaries and the activities of the sponsoring organisations are published alongside research.会议报告、评论以及主办机构的活动，与研究论文并列发表。

History

• ALTEX was established in 1984 by the Fonds fuer Versuchstierfreie Forschung, now known as Animalfree Research.（ALTEX）由动物实验替代研究基金于 1984 年创办，该机构今称（Animalfree Research）。
• It began as a German-language publication titled Alternativen zu Tierexperimenten, with a separate German ISSN, before moving to English.本刊起初是以德语出版的（Alternativen zu Tierexperimenten），另有独立的德文（ISSN），其后转为英文出版。
• The journal became the official organ of the Center for Alternatives to Animal Testing and of partner bodies including EUSAAT and the Doerenkamp-Zbinden Chairs.本刊成为（Center for Alternatives to Animal Testing）以及（EUSAAT）、（Doerenkamp-Zbinden Chairs）等伙伴机构的官方刊物。
• It has been published quarterly by Spektrum Akademischer Verlag, part of Springer, though the publisher cooperation ended at the start of 2026.本刊由（Springer）旗下的（Spektrum Akademischer Verlag）按季出版，不过出版合作已于 2026 年初结束。
• Sonja von Aulock has served as editor-in-chief and signs the journal's editorials.（Sonja von Aulock）担任主编，并署名本刊的社论。
• Its impact factor stood at 6.25 in 2022 and 5.5 in 2025, and the journal is indexed in the Science Citation Index Expanded.其影响因子在 2022 年为 6.25，2025 年为 5.5，本刊被（Science Citation Index Expanded）收录。

Editors

• Sonja von Aulock leads the journal, working with an associate editor and a broad international board of toxicologists and cell biologists.（Sonja von Aulock）主持本刊，与一位副编辑及由毒理学家与细胞生物学家组成的广泛国际编委会协同工作。
• Submissions are peer reviewed, and the journal expects authors to state clearly how their method replaces or reduces animal use.稿件经同行评审，本刊要求作者明确说明其方法如何替代或减少动物使用。
• As a fully open access journal it publishes under a Creative Commons Attribution licence.作为完全开放获取期刊，本刊以知识共享署名许可发表文章。
• The journal publishes research articles, reviews, meeting reports and short commentaries on policy.本刊发表研究论文、综述、会议报告以及关于政策的短评。
• Corners and Food for thought contributions give space to argument and opinion alongside empirical work.（Corners）与（Food for thought）栏目在实证研究之外，为论证与观点提供空间。
• The journal hosts an events calendar and, with CAAT, awards recognising advances in the three Rs.本刊与（CAAT）合作设立活动日历，并颁发表彰三 R 原则进展的奖项。